Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Blood Studies for Cardiovascular System III: Serum Lipid Profile01:25

Blood Studies for Cardiovascular System III: Serum Lipid Profile

Understanding serum lipids is crucial for maintaining cardiovascular health and preventing heart disease and stroke.
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
Cholesterol: Significance and Regulation01:29

Cholesterol: Significance and Regulation

Although not a source of energy, cholesterol plays a significant role as a foundational structure for bile salts, steroid hormones, and vitamin D, as well as being a crucial component of plasma membranes. Approximately 15% of blood cholesterol is derived from our diet, with the remainder synthesized from acetyl CoA by the liver and intestines. Cholesterol is eliminated from the body through its conversion into bile salts, which are eventually discarded in the feces.
Considering cholesterol and...
Lipids: Dietary Sources and Requirements01:18

Lipids: Dietary Sources and Requirements

Lipids are an essential component of a balanced human diet. Triglycerides, which make up the majority of dietary lipids, are found in both saturated fats—commonly present in meat, dairy products, and certain tropical plants like coconut, and hydrogenated oils such as margarine and baking shortenings (trans fats)—and unsaturated fats, which are abundant in seeds, nuts, olive oil, and most vegetable oils. The main sources of cholesterol include egg yolks, various meats and organ meats, shellfish,...
Coronary Artery Disease IV: Preventive Measures01:26

Coronary Artery Disease IV: Preventive Measures

Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
Lipid-Lowering Drugs: Statins and Miscellaneous Agents01:20

Lipid-Lowering Drugs: Statins and Miscellaneous Agents

Hyperlipidemia, a medical condition often referred to as high cholesterol, is characterized by abnormally elevated levels of lipids in the bloodstream. When present in excess, these lipids, specifically cholesterol and triglycerides, can lead to serious health complications, often involving cardiovascular diseases. Illnesses like atherosclerosis, heart attacks, and pancreatitis have all been linked to untreated hyperlipidemia. This means controlling and regulating cholesterol and triglyceride...
Atherosclerosis I: Introduction01:30

Atherosclerosis I: Introduction

Atherosclerosis is a progressive disorder characterized by the buildup of plaques on the arterial inner wall, causing them to narrow and harden over time. These plaques comprise lipids, calcium, blood components, carbohydrates, and fibrous tissue. The process primarily affects the intima of large and medium-sized arteries, reducing blood flow in any artery.Etiology and risk factorsThe cause of atherosclerosis is multifactorial, involving a complex interplay among endothelial injury, lipid...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multifunctional niosome-chitosan-gold nanohybrids for pH/ROS-triggered camptothecin release in breast cancer treatment.

Bioorganic chemistry·2026
Same author

Liver Transplantation for Inherited Metabolic Disorders: A Work in Progress.

Acta paediatrica (Oslo, Norway : 1992)·2026
Same author

Evaluation of Four Novel Biomarkers for Diagnosing of Normoalbuminuric Diabetic Nephropathy in a South Indian Population.

Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia·2025
Same author

Sustainable electronic waste management framework for academic institutions in India.

Scientific reports·2025
Same author

A complicated tale of a cited complication!

Revista espanola de anestesiologia y reanimacion·2025
Same author

To Determine the Efficacy of Balloon Sinuplasty over Conventional Functional Endoscopic Sinus Surgery.

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India·2025
Same journal

Development and Validation of a Comprehensive Obesity Assessment Tool: Integrating Lifestyle, Body Image, and Past Weight Management.

Indian journal of endocrinology and metabolism·2026
Same journal

The Indian Obesity Paradox- Low in Muscle, High in Fat.

Indian journal of endocrinology and metabolism·2026
Same journal

Serial Changes in Thyroid Hormones with Oral or Intravenous Bisphosphonates.

Indian journal of endocrinology and metabolism·2026
Same journal

Role of Serum Triiodothyronine-to-Thyroxine Ratio and Thyroid Colour Flow Doppler in Differentiation of Graves' Disease from Destructive Thyroiditis.

Indian journal of endocrinology and metabolism·2026
Same journal

Efficacy of Fixed Low-Dose Weekly Subcutaneous Testosterone Self-Administration in Transgender Male Patients in India.

Indian journal of endocrinology and metabolism·2026
Same journal

What Works in Type 2 Diabetes: Intermittent Fasting or Calorie Restriction or Both?

Indian journal of endocrinology and metabolism·2026
See all related articles

Related Experiment Video

Updated: May 12, 2026

High-Density Lipoprotein-Specific Phospholipid Efflux Assay
07:08

High-Density Lipoprotein-Specific Phospholipid Efflux Assay

Published on: September 30, 2025

High-density lipoprotein cholesterol: How High.

G Rajagopal1, V Suresh, Alok Sachan

  • 1Department of Endocrinology and Metabolism, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh - 517 507, India .

Indian Journal of Endocrinology and Metabolism
|April 9, 2013
PubMed
Summary
This summary is machine-generated.

High-density lipoprotein cholesterol (HDL-C), the "good cholesterol," is inversely linked to coronary heart disease (CHD) risk. Higher HDL-C levels are associated with significantly lower CHD risk, with no identified upper limit for this protective effect.

Keywords:
High-density lipoprotein cholesterolcardiovascular riskcholesteryl ester transfer protein inhibitors

More Related Videos

Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein
07:29

Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein

Published on: October 12, 2017

Related Experiment Videos

Last Updated: May 12, 2026

High-Density Lipoprotein-Specific Phospholipid Efflux Assay
07:08

High-Density Lipoprotein-Specific Phospholipid Efflux Assay

Published on: September 30, 2025

Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein
07:29

Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein

Published on: October 12, 2017

Area of Science:

  • Cardiovascular Medicine
  • Lipid Metabolism
  • Preventive Cardiology

Background:

  • High-density lipoprotein cholesterol (HDL-C) is recognized as

Purpose of the Study:

  • To review the relationship between HDL-C levels and coronary heart disease (CHD) risk.
  • To discuss the implications for treating low HDL-C and the role of emerging therapies.

Main Methods:

  • Review of epidemiological studies correlating HDL-C levels with CHD risk.
  • Analysis of the established benefits of statins.
  • Overview of cholesteryl ester transfer protein (CETP) inhibitors in HDL metabolism.

Main Results:

  • A clear inverse relationship exists between HDL-C levels and CHD risk.
  • Higher HDL-C concentrations (above 60 mg/dL) are associated with progressively lower CHD risk.
  • No upper limit for the beneficial effect of HDL-C on CHD risk has been determined.

Conclusions:

  • Elevated HDL-C levels are protective against coronary heart disease.
  • While statins improve CHD outcomes, the therapeutic targets for low HDL-C remain under investigation.
  • Cholesteryl ester transfer protein (CETP) inhibitors are a potential therapeutic avenue, but their clinical utility requires further evaluation.