Related Experiment Video

Updated: May 12, 2026

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
06:46

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19

Published on: July 5, 2022

Diabetes in young: Beyond type 1

Anju Virmani1, Abhishek Kulkarni

  • 1Department of Endocrinology and Metabolism, Senior Consultant Endocrinologist, Apollo/ Max/ Pentamed/ Sunderlal Jain Hospitals, Delhi, India.

Indian Journal of Endocrinology and Metabolism
|April 9, 2013
PubMed

Insights

Childhood diabetes, primarily type 1, sees a rise in type 2 cases due to lifestyle changes. Differentiating between types and other pancreatic conditions presents challenges, highlighting the need for primary prevention.

Area of Science:

  • Pediatrics
  • Endocrinology
  • Public Health

Background:

  • Type 1 diabetes is the most common form in children.
  • Childhood type 2 diabetes is increasing due to lifestyle factors.
  • Diagnostic challenges exist due to overlapping symptoms.

Purpose of the Study:

  • To review the increasing prevalence of type 2 diabetes in children.
  • To discuss diagnostic difficulties in childhood diabetes.
  • To emphasize the importance of primary prevention strategies.

Main Methods:

  • Literature review of childhood diabetes.
  • Analysis of diagnostic criteria for differentiating diabetes types.
  • Discussion of management and prevention.

Main Results:

  • Type 2 diabetes is a growing concern in pediatric populations.
  • Non-specific clinical and laboratory findings complicate diagnosis.
  • Monogenic diabetes (MODY) and other pancreatic diseases can mimic common types.

Conclusions:

  • Accurate diagnosis is crucial for effective childhood diabetes management.
  • Primary prevention of childhood diabetes is paramount.
  • Further research into early detection and intervention is needed.

Keywords:
MODYType 1 diabetestype 2 diabetes

More Related Videos

Accelerated Type 1 Diabetes Induction in Mice by Adoptive Transfer of Diabetogenic CD4+ T Cells06:27

Accelerated Type 1 Diabetes Induction in Mice by Adoptive Transfer of Diabetogenic CD4+ T Cells

Published on: May 6, 2013

Related Concept Videos

Type I Diabetes I: Introduction01:12

Type I Diabetes I: Introduction

Type 1 diabetes mellitus is a chronic metabolic disorder characterized by an absolute deficiency of insulin resulting from the autoimmune destruction of pancreatic β-cells. Although it can occur at any age, it is most commonly diagnosed in childhood, adolescence, or early adulthood. The loss of insulin production impairs cellular glucose uptake, resulting in persistent hyperglycemia and necessitating lifelong insulin therapy.Autoimmune Destruction of β-CellsThe hallmark of type 1 diabetes is an...
Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type I Diabetes II: Pathophysiology01:26

Type I Diabetes II: Pathophysiology

Type 1 diabetes mellitus arises from an immune-mediated destruction of pancreatic β-cells, resulting in an absolute deficiency of insulin. This process develops in genetically susceptible individuals when autoimmunity, environmental exposures, and immunologic dysregulation converge to trigger a targeted attack on the insulin-producing cells of the pancreas. The β-cells are located within the islets of Langerhans and are essential for regulating blood glucose by facilitating cellular uptake of...
Type II Diabetes I: Introduction01:26

Type II Diabetes I: Introduction

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance, in which target tissues such as the liver, muscle, and adipose tissue respond poorly to insulin. It is also associated with inadequate compensatory insulin secretion, where pancreatic β-cells fail to produce sufficient insulin. Together, these abnormalities lead to persistent hyperglycemia.EtiologyT2DM develops through a complex interaction of genetic predisposition and environmental or...
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
Type I Diabetes III: Clinical Manifestations01:19

Type I Diabetes III: Clinical Manifestations

Type 1 diabetes mellitus typically presents with rapid-onset symptoms due to the body’s inability to utilize glucose in the absence of insulin. Since insulin is required for glucose uptake into cells, its deficiency leads to hyperglycemia and cellular energy deprivation, resulting in characteristic clinical features.Polyuria and PolydipsiaOne of the earliest, most prominent symptoms is polyuria (excessive urination). When blood glucose concentrations rise above the renal threshold, the kidneys...