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Related Concept Videos

Regulation of Hormone Secretion01:19

Regulation of Hormone Secretion

Regulation of hormone secretion is a finely tuned orchestration driven by various types of stimuli, encompassing neural, humoral, and hormonal signals. Environmental cues instigate neural stimuli, where action potentials traverse nerve fibers to reach their designated targets. An illustrative scenario is the body's response to stress, wherein the sympathetic nervous system releases epinephrine from the adrenal glands, inducing the well-known 'fight or flight' reaction.
Humoral stimuli,...
Structures of the Endocrine System00:59

Structures of the Endocrine System

The intricate framework of the endocrine system encompasses a diverse array of glands, with their target tissues and organs strategically distributed throughout the body. Central to this network are the endocrine glands, specialized structures that lack ducts and release hormones directly into the interstitial fluid. Notably, the hypothalamus, a vital neuroendocrine organ situated in the brain, governs neural functions and serves as a potent source of hormonal regulation. Near the hypothalamus...
An Overview of the Endocrine System01:10

An Overview of the Endocrine System

The endocrine system, a complex network of glands, orchestrates physiological balance within the body through the production and secretion of hormones. These hormones are chemical messengers in intercellular communication, acting as conduits between the secretory cells and distant target sites. They traverse the circulatory system by being released into the extracellular fluid, and their impact is specific to cells possessing receptors for a particular hormone.
The endocrine system collaborates...
The Endocrine System01:29

The Endocrine System

The endocrine system is an extensive network of glands – organs or tissues in the body that create chemicals that control many bodily functions, that secrete hormones, which are chemical messengers that play essential roles in regulating various bodily functions. These hormones are secreted into the bloodstream and travel throughout the body. They require specific receptors to convey signals to cells possessing these corresponding receptors. This complex signaling mechanism ensures that every...
Endocrine Signaling01:45

Endocrine Signaling

Endocrine cells produce hormones to communicate with remote target cells found in other organs. The hormone reaches these distant areas using the circulatory system. This exposes the whole organism to the hormone but only those cells expressing hormone receptors or target cells are affected. Thus, endocrine signaling induces slow responses from its target cells but these effects also last longer.
Endocrine Signaling01:45

Endocrine Signaling

Endocrine cells produce hormones to communicate with remote target cells found in other organs. The hormone reaches these distant areas using the circulatory system. This exposes the whole organism to the hormone but only those cells expressing hormone receptors or target cells are affected. Thus, endocrine signaling induces slow responses from its target cells but these effects also last longer.

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Human Pseudoislet System for Synchronous Assessment of Fluorescent Biosensor Dynamics and Hormone Secretory Profiles
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Endocrine labomas.

Deep Dutta1, Subhankar Chowdhury

  • 1Department of Endocrinology and Metabolism, IPGMER and SSKM Hospital, 244 AJC Bose Road, Kolkata, India.

Indian Journal of Endocrinology and Metabolism
|April 9, 2013
PubMed
Summary
This summary is machine-generated.

Interpreting laboratory endocrinology requires awareness of assay challenges. Understanding hormone testing pitfalls, like lack of standardization, is crucial for accurate diagnosis and patient care.

Keywords:
EndocrinologyLabomaslaboratorypitfalls

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Area of Science:

  • Endocrinology
  • Clinical Laboratory Science

Background:

  • Laboratory diagnostics are fundamental to modern endocrinology.
  • Endocrinology relies heavily on accurate hormone assays for diagnosis and management.

Purpose of the Study:

  • To highlight challenges and pitfalls in laboratory endocrinology.
  • To emphasize the importance of understanding hormone assay interpretation for clinicians.

Main Methods:

  • Review of common issues in endocrine hormone testing.
  • Discussion of pre-analytical and analytical factors affecting hormone assays.

Main Results:

  • Lack of standardization and rigorous implementation are significant challenges in endocrine assays.
  • Specific assays like prolactin, thyroglobulin, steroid hormones, renin, and vitamin D present interpretation difficulties.

Conclusions:

  • Awareness of assay methodologies, pre-analytical requirements, and disease-specific analytical issues is essential.
  • Addressing laboratory endocrinology challenges can prevent patient and physician concern and unnecessary investigations.