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Thyroid dysfunction in type 2 diabetes mellitus: A retrospective study.

Laloo Demitrost1, Salam Ranabir

  • 1Department of Medicine, Regional Institute of Medical Sciences, Imphal, Manipur, India.

Indian Journal of Endocrinology and Metabolism
|April 9, 2013
PubMed
Summary
This summary is machine-generated.

Thyroid dysfunction, particularly hypothyroidism, is common in type 2 diabetes patients over 45. Higher BMI increases this risk, highlighting the need for screening in this population.

Keywords:
TSHthyroid dysfunctiontype 2 DM

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Area of Science:

  • Endocrinology
  • Metabolic Disorders

Background:

  • Type 2 diabetes mellitus (DM) is a significant health concern.
  • A potential link between type 2 DM and thyroid dysfunction exists, but prevalence data is lacking.

Purpose of the Study:

  • To determine the prevalence of thyroid dysfunction among type 2 DM patients in Manipur, India.

Main Methods:

  • Retrospective analysis of 202 type 2 DM patients from January 2011 to July 2012.
  • Inclusion criteria: known type 2 DM; Exclusion criteria: prior hypothyroidism or thyroid-affecting medications.
  • Thyroid stimulating hormone (TSH) levels were investigated.

Main Results:

  • Out of 202 patients, 139 (68.8%) were euthyroid.
  • Hypothyroidism (subclinical and clinical) was observed in 56 patients (27.7%), with a peak in the 45-64 age group.
  • Increased BMI (>25) was significantly associated with a higher risk of hypothyroidism (P < 0.016).

Conclusions:

  • Hypothyroidism prevalence is notably high in type 2 DM patients over 45 years.
  • Overweight or obese type 2 DM patients (BMI > 25) face an elevated risk of hypothyroidism.
  • These findings suggest the importance of thyroid function screening in specific type 2 DM patient groups.