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Recurrent stroke as a presenting feature of acquired partial lipodystrophy
Namburi R Prasad1, Ponnala A Reddy, Bindu Menon
1Department of Endocrinology, Narayana Medical College, & Hospital, ChinthareddyPalem, Nellore, District, Andhra Pradesh, India.
Indian Journal of Endocrinology and Metabolism
|April 9, 2013
Summary
Acquired partial lipodystrophy (PL) is a rare condition causing fat loss. This case highlights its association with serious health issues like stroke in a teenage girl.
Area of Science:
- Endocrinology
- Genetics
- Immunology
Background:
- Acquired partial lipodystrophy (PL), also known as Barraquer-Simons syndrome, is a rare disorder.
- It typically manifests in childhood with a progressive, head-to-toe loss of subcutaneous fat.
Observation:
- This report details a 16-year-old female patient experiencing gradual facial fat loss since age three.
- The patient presented with recurrent left hemiparesis and academic decline, leading to school withdrawal.
Findings:
- Acquired PL can be associated with systemic lupus erythematosus (SLE), anticardiolipin antibodies, hypothyroidism, diabetes, and dyslipidemia.
- These comorbidities increase the risk of severe complications, including cerebrovascular stroke and cardiovascular disease.
Implications:
- Early recognition and management of acquired PL are crucial for preventing associated systemic complications.
- This case underscores the importance of a multidisciplinary approach in managing patients with rare lipodystrophic syndromes and their comorbidities.
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