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Updated: May 12, 2026

Pathological Analysis of Lung Metastasis Following Lateral Tail-Vein Injection of Tumor Cells
Published on: May 20, 2020
Non small-cell lung cancer with metastasis to thigh muscle and mandible: two case reports
Francesca Maria Giugliano1, Domingo Alberti, Giovanna Guida
1Radiation Therapy Department, National Cancer Institute, Pascale Foundation, Naples, Italy. francesca_giugliano@hotmail.com.
Introduction:
Lung cancer is the leading cause of cancer-related death in Europe and the US. Isolated metastases to skeletal muscle and the mandible are very uncommon.
Case Presentation:
This report presents two cases. Case 1 concerns a 45-year-old Caucasian woman affected by muscle metastasis of the right thigh from non-small-cell lung cancer. Case 2 concerns a 61-year-old Caucasian man affected by mandible metastasis from non-small-cell lung cancer. Both metastases were detected by diagnostic imaging studies. Both patients were treated with radiation therapy with palliative and antalgic intent.
Conclusion:
Radiation therapy was effective and well tolerated in both cases. Both our patients are alive, with follow-up of 18 months and five months, respectively.
