[Morphofunctional changes in brain neurons during emotional stress]

It is shown that the strong emotional immobilization stress in rats resulted in increased blood-brain barrier permeability and besides--in brain parenchymal vessels damages accompanied by haemorrhages and the loss of some nerve cells. The earliest and strongest brain vessel disruptions under emotional stress were found in the oral part of the brain stem reticular formation. The vessel disturbances and the damages of the neurons were found for a long time interval after immobilization stress and resulted in functional, behavioral changes and immune reactions. Locus ceruleus was found to be involved in the blood-brain barrier function regulation and due to the fact in the fortune of the neurons under the emotional stress.