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[Haemophilus meningitis in properly vaccinated children: report of three cases]

Z Metreau1, H Le Bars, M Desgranges-Federico

  • 1Urgences pédiatriques, hôpital Sud, CHU de Rennes, 16, boulevard de Bulgarie, 35000 Rennes, France. zofia.metreau@chu-rennes.fr

Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|April 10, 2013
PubMed

Insights

Even with vaccination, Haemophilus influenzae type b (Hib) meningitis persists in children. This study highlights the continued circulation of Hib strains despite widespread immunization programs.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Vaccinology

Context:

  • The widespread vaccination against Haemophilus influenzae type b (Hib) in France since 1993 has significantly reduced invasive Hib infections.
  • Despite high vaccination coverage and booster doses, rare cases of Hib meningitis continue to occur.

Purpose:

  • To report on three cases of Hib meningitis in vaccinated children observed between 2007 and 2010.
  • To emphasize the ongoing risk of Hib meningitis in vaccinated populations and the continued circulation of Hib strains.

Summary:

  • Three cases of Haemophilus influenzae type b meningitis were documented in vaccinated infants and children aged 9, 14, and 29 months at Rennes University Hospital.
  • All patients experienced satisfactory recovery without detectable immune deficiency.
  • These cases occurred during winter seasons, indicating persistent circulation of Hib.

Impact:

  • Demonstrates that a residual risk of Hib meningitis exists in infants and children, even those who are vaccinated.
  • Highlights the importance of continued surveillance for Hib infections and potential strain circulation in the general population.
  • Reinforces the need to evaluate long-term vaccine effectiveness and public health strategies against vaccine-preventable diseases.

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