Related Experiment Video
Updated: May 12, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
[A rare ventricular septal defect: a case report]
Maria Francesca Notarangelo1, Federico Bontardelli, Umberto Taliani
1U.O.C. di Cardiologia, Dipartimento Cardio-Nefro-Polmonare, Azienda Ospedaliero-Universitaria di Parma. francescanotarangelo@yahoo.it
Insights
The Gerbode defect, a rare heart communication, can now be closed non-surgically. This case report details successful percutaneous closure of a left ventricular-right atrial communication using an Amplatzer device, improving patient outcomes.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Surgery
Background:
- Left ventricular-right atrial communications, or Gerbode defects, are rare congenital or acquired ventricular septal defects.
- Acquired Gerbode defects can arise from cardiac surgery, endocarditis, trauma, or myocardial infarction.
- Surgical correction historically carried high mortality rates.
Observation:
- A 69-year-old patient presented with a left ventricular-right atrial communication secondary to mitral valve surgery.
- Diagnosis was confirmed using transesophageal and real-time three-dimensional echocardiography.
- The defect was successfully closed percutaneously with an Amplatzer device.
Findings:
- Transcatheter closure of the Gerbode defect resulted in no residual flow.
- The patient experienced significant clinical improvement post-procedure.
- Percutaneous closure offers a less invasive alternative to surgery for these rare defects.
Implications:
- Percutaneous closure represents a safe and effective treatment for acquired Gerbode defects.
- This approach may reduce the morbidity and mortality associated with surgical repair.
- Echocardiography is crucial for accurate diagnosis and procedural guidance.
Abstract:
Left ventricular-right atrial communications, known collectively as the Gerbode defect, are rare types of ventricular septal defects. Acquired forms of this defect have been described as a complication of cardiac surgery, bacterial endocarditis, chest trauma, or myocardial infarction. Diagnosis of this rare defect is challenging, but can be confirmed with echocardiography or cardiac magnetic resonance imaging. Until 6 years ago, these communications were corrected only surgically, often with relatively high mortality. However, few case reports of transcatheter closures of the defects have recently been reported with excellent results. We describe a 69-year-old patient with left ventricular-right atrial communication secondary to mitral valve surgery. The diagnosis was made by transesophageal and real-time three-dimensional echocardiography. The defect was closed percutaneously using an Amplatzer device. At follow-up, there was no residual flow and the patient improved clinically.
Related Concept Videos
Mitral Stenosis I: Introduction
Aortic Regurgitation I: Introduction
Mitral Regurgitation I: Introduction
Cardiovascular System Abnormal Findings II: Auscultation
Abnormal Heart Sounds
Gallops:
Mitral Stenosis II: Clinical features and Diagnostic Tests
Aortic Regurgitation II: Clinical Features and Diagnostic Tests

