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Comparative Lesions Analysis Through a Targeted Sequencing Approach
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Comparative Lesions Analysis Through a Targeted Sequencing Approach

Published on: November 5, 2019

How do we approach the goal of identifying everybody with Lynch syndrome?

Heather Hampel1, Albert de la Chapelle

  • 1The Ohio State University, Columbus, OH, USA. Heather.Hampel@osumc.edu

Familial Cancer
|April 10, 2013
PubMed
Abstract

No abstract available in PubMed .

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Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...