Related Experiment Video
Updated: May 12, 2026

Assays for the Specific Growth Rate and Cell-binding Ability of Rotavirus
Published on: January 28, 2019
[A rare cause of afebrile convulsion: rotavirus gastroenteritis]
Müsemma Karabel1, Duran Karabel, Semra Kara
1Department of Pediatrics, Fatih University, Faculty of Medicine, Ankara, Türkiye. musemma.alagoz@gmail.com
Insights
Rotavirus gastroenteritis can cause afebrile seizures in children, even healthy ones. This highlights the diverse clinical presentations of rotavirus infections beyond typical diarrhea.
Area of Science:
- Pediatrics
- Infectious Diseases
- Neurology
Background:
- Rotavirus is a leading cause of infectious diarrhea in young children, responsible for significant mortality and morbidity.
- Common complications include severe dehydration and electrolyte imbalance.
- Extraintestinal manifestations of rotavirus infection are considered rare.
Observation:
- Recent reports indicate a correlation between rotavirus gastroenteritis and afebrile seizures.
- These seizures occur without accompanying encephalopathy, dehydration, electrolyte imbalance, or hypoglycemia.
- The study emphasizes that rotavirus infections can present with varied clinical signs.
Findings:
- Rotavirus infections are prevalent in the region studied.
- Afebrile seizures represent an unusual clinical manifestation of rotavirus gastroenteritis.
- The condition can affect both infants with underlying health issues and healthy infants.
Implications:
- Clinicians should consider rotavirus infection in the differential diagnosis of afebrile seizures in children.
- Awareness of these varied presentations is crucial for timely diagnosis and management.
- Further research may elucidate the mechanisms linking rotavirus to neurological symptoms.
Abstract:
Rotavirus is the most common infectious diarrhea that causes important mortality and morbidities in small children, severe dehydration and electrolyte imbalance. Extraintestinal signs are rare in rotavirus infections. Recently, afebrile seizures associated with rotavirus gastroenteritis but without encephalopathy, dehydration, electrolyte imbalance or hypoglycemia have being reported. In this article, the fact that rotavirus, which is seen commonly in our country, can be confronted with various clinical manifestations was emphasized by reminding that it can be seen not only in infants with neurologic and systemic disease but also in healthy infants.
More Related Videos
08:01Live Calcium Imaging of Virus-Infected Human Intestinal Organoid Monolayers Using Genetically Encoded Calcium Indicators
Published on: January 19, 2024
05:51Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain
Published on: July 24, 2016
Related Concept Videos
Encephalitis l: Introduction
Viral Meningitis
Bacterial Gastroenteritis
Bacterial Meningitis I: Introduction
Types of Fever
Here are the different types of fever:
Arboviral Encephalitis