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Related Concept Videos

Phosphate Buffer01:22

Phosphate Buffer

The phosphate buffer system is a critical biological mechanism for maintaining pH stability in the body. This system operates primarily through two components: sodium dihydrogen phosphate (NaH2PO4), which acts as a weak acid, and sodium hydrogen phosphate (Na2HPO4), which serves as a weak base.
Sodium dihydrogen phosphate does not fully dissociate in neutral or acidic solutions. When a strong base, such as sodium hydroxide (NaOH), is introduced into the solution, sodium dihydrogen phosphate...
Introduction to Electrolytes01:33

Introduction to Electrolytes

In humans, electrolytes play a vital role in various physiological processes. Balancing electrolyte levels is essential for normal body functions; their imbalance can be life-threatening. The major electrolytes include sodium, potassium, chloride, calcium, phosphate, and bicarbonate. They are primarily involved in physiological processes, such as nerve signal transmission, membrane trafficking, muscle contraction, buffering body fluids, and balancing water levels in the body.
Role of Sodium
One...
Roles of Electrolytes: Calcium and Phosphate01:27

Roles of Electrolytes: Calcium and Phosphate

Calcium and phosphate are essential electrolytes in the human body, with calcium being the most abundant mineral. Around 99% of the body's calcium is stored in the skeleton and teeth, forming a crystal lattice of mineral salts in combination with phosphates. Calcium plays crucial roles in various bodily functions such as blood clotting, neurotransmitter release, muscle tone maintenance, and nervous and muscle tissue excitability.
The calcium concentration in blood plasma is primarily regulated...
Phosphorylation01:02

Phosphorylation

The addition or removal of phosphate groups from proteins is the most common chemical modification that regulates cellular processes. These modifications can affect the structure, activity, stability, and localization of proteins within cells as well as their interactions with other proteins.
During phosphorylation, protein kinases transfer the terminal phosphate group of ATP to specific amino acid side chains of substrate proteins. Serine, threonine, and tyrosine are the most commonly...
Impact of Pharmacokinetic–Pharmacodynamic Models: Regulatory Decisions01:15

Impact of Pharmacokinetic–Pharmacodynamic Models: Regulatory Decisions

PK–PD modeling has significantly influenced FDA regulatory decisions, particularly drug approval, dosage optimization, and labeling. These models integrate pharmacokinetics (PK) and pharmacodynamics (PD) to predict drug behavior and effects, aiding in optimizing dosing regimens and enhancing the probability of clinical trial success.One notable example is Nesiritide (Natrecor®), a recombinant human brain natriuretic peptide for treating acute decompensated congestive heart failure (CHF).
Peritoneal Dialysis III: Nursing Management01:25

Peritoneal Dialysis III: Nursing Management

Peritoneal dialysis, or PD, utilizes the peritoneal membrane as a filter to eliminate excess fluid and waste products. Effective nursing management is essential for ensuring patient safety, preventing complications, and promoting optimal function of the peritoneal dialysis process.Assessment and MonitoringNurses must thoroughly assess the patient before, during, and after each dialysis session. Regular monitoring includes vital signs, daily weight, fluid intake and output, and laboratory values...

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Updated: May 12, 2026

Assaying for Inorganic Polyphosphate in Bacteria
07:20

Assaying for Inorganic Polyphosphate in Bacteria

Published on: January 21, 2019

Sodium phosphate as an ergogenic aid.

Christopher L Buck1, Karen E Wallman, Brian Dawson

  • 1School of Sport Science, Exercise and Health, The University of Western Australia, 35 Stirling Highway, Crawley, WA, 6009, Australia. buckc01@student.uwa.edu.au

Sports Medicine (Auckland, N.Z.)
|April 10, 2013
PubMed
Summary

Sodium phosphate supplementation may enhance athletic performance by improving aerobic capacity and power output. Further research is needed to optimize dosing and investigate gender-specific effects of this ergogenic aid.

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Optimized Procedure for Determining the Adsorption of Phosphonates onto Granular Ferric Hydroxide using a Miniaturized Phosphorus Determination Method
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Optimized Procedure for Determining the Adsorption of Phosphonates onto Granular Ferric Hydroxide using a Miniaturized Phosphorus Determination Method

Published on: May 18, 2018

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Last Updated: May 12, 2026

Assaying for Inorganic Polyphosphate in Bacteria
07:20

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Optimized Procedure for Determining the Adsorption of Phosphonates onto Granular Ferric Hydroxide using a Miniaturized Phosphorus Determination Method
08:21

Optimized Procedure for Determining the Adsorption of Phosphonates onto Granular Ferric Hydroxide using a Miniaturized Phosphorus Determination Method

Published on: May 18, 2018

Area of Science:

  • Sports Science
  • Nutritional Biochemistry
  • Exercise Physiology

Background:

  • Nutritional ergogenic aids offer athletes performance enhancements beyond training.
  • Sodium phosphate is an emerging supplement showing potential benefits for athletic performance.

Purpose of the Study:

  • To critically review the ergogenic effects of sodium phosphate.
  • To identify areas for future research regarding sodium phosphate supplementation.

Main Methods:

  • Review of existing literature on sodium phosphate as an ergogenic aid.
  • Analysis of reported doses, protocols, and participant characteristics in supplementation studies.

Main Results:

  • Sodium phosphate supplementation is associated with increased aerobic capacity, peak power output, and anaerobic threshold.
  • Potential mechanisms include enhanced 2,3-Diphosphoglycerate (2,3-DPG) levels, improved myocardial efficiency, and increased ATP/phosphocreatine synthesis.

Conclusions:

  • Evidence suggests sodium phosphate can be an effective ergogenic aid.
  • Variability in study protocols and limited research on gender effects necessitate further investigation.