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Updated: May 12, 2026
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Chemically-blocked Antibody Microarray for Multiplexed High-throughput Profiling of Specific Protein Glycosylation in Complex Samples
Published on: May 4, 2012
Profiling glycosyltransferase activities by tritium imaging of glycan microarrays
Sonia Serna1, Cornelis H Hokke, Martin Weissenborn
1Biofunctional Nanomaterials Unit, CIC biomaGUNE, P° de Miramón 182, Parque Tecnológico, 20009 San Sebastian, Spain.
Chembiochem : a European Journal of Chemical Biology
|April 10, 2013
Abstract:
High-throughput microarray technology has been combined with ultrasensitive and high-resolution tritium autoradiography to create a new platform for the quantitative detection of glycosyltransferase activity on glycan arrays. In addition, we show full compatibility with the use of fluorescently labeled lectins to help with the stereochemical assignment of newly formed glycoside linkages.
