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Hemolytic-uremic syndrome following "crack" cocaine inhalation
J A Tumlin1, J M Sands, A Someren
1Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30322.
The American Journal of the Medical Sciences
|June 1, 1990
Abstract:
The authors present a patient who experienced cocaine-related thrombotic microangiopathy and patchy renal cortical necrosis, associated with the clinical syndrome of microangiopathic hemolytic anemia, thrombocytopenia and acute renal failure, characteristics of the Hemolytic-Uremic syndrome. The proposed pathogenetic mechanisms include: (1) cocaine-induced vasoconstriction and endothelial damage and (2) procoagulant effects of cocaine.