Related Experiment Video
Updated: May 12, 2026

Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain Injury
Published on: August 14, 2019
Susceptibility weighted imaging depicts retinal hemorrhages in abusive head trauma
Giulio Zuccoli1, Ashok Panigrahy, Anshul Haldipur
1Department of Pediatric Radiology, Children's Hospital of Pittsburgh of UPMC, 4401 Penn Avenue, Pittsburgh, PA 15224, USA. giulio.zuccoli@gmail.com
Introduction:
This study aims to evaluate the capability of magnetic resonance imaging (MRI) susceptibility weighted images (SWI) in depicting retinal hemorrhages (RH) in abusive head trauma (AHT) compared to the gold standard dilated fundus exam (DFE).
Methods:
This is a retrospective, single institution, observational study on 28 patients with suspected AHT, who had a DFE and also underwent brain MRI-SWI as part of routine diagnostic protocol. Main outcome measures involved evaluation of patients to determine whether the RH could be identified on standard and high-resolution SWI sequences.
Results:
Of the 21 subjects with RH on DFE, 13 (62%) were identified by using a standard SWI sequence performed as part of brain MRI protocols. Of the 15 patients who also underwent an orbits SWI protocol, 12 (80%) were positive for RH. None of the seven patients without RH on of DFE had RH on either standard or high-resolution SWI. Compared with DFE, the MRI standard protocol showed a sensitivity of 75% which increased to 83% for the orbits SWI protocol.
Conclusions:
Our study suggests the usefulness of a tailored high-resolution orbits protocol to detect RH in AHT.
Insights
Magnetic resonance imaging (MRI) susceptibility weighted images (SWI) can detect retinal hemorrhages (RH) in abusive head trauma (AHT). A specialized high-resolution orbits SWI protocol improves RH detection compared to standard brain MRI protocols.
Area of Science:
- Ophthalmology
- Radiology
- Pediatrics
Background:
- Abusive head trauma (AHT) often presents with retinal hemorrhages (RH).
- Diagnosing AHT relies on identifying RH, typically via dilated fundus examination (DFE).
- Magnetic resonance imaging (MRI) susceptibility weighted imaging (SWI) is a non-invasive technique that may detect RH.
Purpose of the Study:
- To evaluate the effectiveness of MRI SWI in detecting RH in suspected AHT cases.
- To compare the diagnostic capability of standard brain MRI SWI sequences versus a dedicated high-resolution orbits SWI protocol for RH detection.
- To assess the sensitivity and specificity of MRI SWI for RH identification against the gold standard DFE.
Main Methods:
- Retrospective, observational study of 28 patients with suspected AHT.
- DFE and brain MRI-SWI were performed on all patients.
- Standard and high-resolution orbits SWI sequences were analyzed for RH detection.
Main Results:
- Standard brain MRI-SWI detected RH in 62% of patients with RH confirmed by DFE.
- A dedicated orbits SWI protocol increased RH detection to 80%.
- MRI SWI showed 75% sensitivity with standard protocols, increasing to 83% with the orbits protocol; no RH were detected in patients without DFE-confirmed RH.
Conclusions:
- MRI SWI is a valuable tool for detecting RH in AHT.
- A tailored, high-resolution orbits SWI protocol enhances the detection rate of RH.
- MRI SWI, particularly with an orbits protocol, shows promise as a supplementary diagnostic method for AHT.
Related Concept Videos
Hemorrhagic Stroke ll: Pathophysiology
Hemorrhagic Stroke l: Introduction

