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Published on: August 19, 2021
Prostate cancer presenting as cervical lymphadenopathy
Siddharth P Dubhashi1, Harsh Kumar, Sandeep R Nath
1Padmashree Dr D Y Patil Medical College, Pimpri Pune, Maharashtra, India.
The American Journal of Case Reports
|April 10, 2013
Summary
Prostate cancer can present as generalized lymphadenopathy in older men. Early diagnosis using PSA staining and effective treatment with hormonal therapy are crucial, even in advanced stages.
Area of Science:
- Oncology
- Urology
Background:
- Prostate cancer is a prevalent malignancy in men, particularly over 50.
- Metastasis commonly affects bone and lymph nodes.
- It is the second-leading cause of cancer death in men.
Purpose of the Study:
- To report a case of prostate cancer presenting atypically with cervical lymphadenopathy.
- To highlight the diagnostic utility of PSA staining and the efficacy of hormonal therapy.
Main Methods:
- Case report of an elderly male with cough and cervical lymphadenopathy.
- Lymph node cytology and immunohistochemistry with PSA staining were performed.
- Treatment involved androgen blockade therapy.
Main Results:
- Immunohistochemistry confirmed adenocarcinoma of prostatic origin.
- The patient showed a dramatic response to androgen blockade therapy.
- Chest infiltrates and lymph nodes regressed within six months.
Conclusions:
- Prostate cancer should be considered in males with unexplained adenocarcinoma and lymphadenopathy.
- PSA staining is vital for confirming prostatic origin.
- Hormonal therapy is effective for advanced prostate cancer.
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