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Hypertriglyceridemia: a case report from diagnostic laboratory, Barasat, West Bengal, India
Utpal Kumar Biswas1, Arun Kumar
1Medicave Diagnostic Center Private Limited Barasa.
Insights
This case report highlights a 40-year-old man with severe hypertriglyceridemia despite a healthy lifestyle. The findings suggest a higher risk of dyslipidemia and coronary artery disease (CAD) in males aged 31-40.
Area of Science:
- Cardiology
- Metabolic Disorders
Background:
- Hypertriglyceridemia, an abnormal blood triglyceride concentration, is linked to atherosclerosis.
- Early detection and management are crucial, especially in asymptomatic individuals.
Observation:
- A 40-year-old man with a healthy lifestyle presented with severe hypertriglyceridemia (372 mg/dL).
- Biochemical analysis revealed elevated fasting glucose (186 mg/dL) and a high Cholesterol/HDL-C ratio (23.6:1).
- Despite normal blood pressure and a BMI of 27, his lipid profile indicated dyslipidemia.
Findings:
- The study identified an increased prevalence of dyslipidemia in males aged 31-40.
- This demographic may face a heightened risk of developing coronary artery disease (CAD) and experiencing premature myocardial infarction.
- The case underscores the importance of routine screening for dyslipidemia in this age group.
Implications:
- Combination lifestyle therapies, including diet and exercise, are vital for managing dyslipidemia.
- Early therapeutic intervention alongside lifestyle modifications can help prevent cardiovascular events.
- This case emphasizes the need for increased awareness and proactive screening for dyslipidemia in at-risk populations.
Abstract:
Hypertriglyceridemia is defined as an abnormal concentration of triglyceride in the blood and has been associated with atherosclerosis, even in the absence of hypercholesterolemia. This case report is of 40-year-old man diagnosed to have hypertriglyceridemia who attended for routine screening in our diagnostic laboratory at Barasat. He was nonsmoker, non-alcoholic, had a reasonable diet with abundant fruits and vegetables, and was on regular exercise. He was not taking any lipid lowering medications. He hailed from Barasat, and was employed in Government sector in Barasat and policeman by profession. His father died at the age of 57 years in a heart attack; but his mother is healthy and now almost 62 years of age, and he has two brothers one elder and another younger to him, both are healthy. His blood pressure was normal, his body-mass index was 27, and his waist circumference was 96 cm and hip circumference was 103. His waist/hip ratio was 0.932. The Biochemical analyses were as follows- Fasting Glucose: 186 mg/dL, Total Cholesterol: 90 mg/dL, Triglycerides: 372 mg/dL, High-density cholesterol: 3.80 mg/dL, Low-density cholesterol: 2.90 mg/dL, VLDL: 83.20 mg/dL, Cholesterol/HDL-C ratio: 23.6:1, LDL-C/HDL-C: 0.07:1. This study revealed the increased prevalence of dyslipidemia to be more prevalent in 31-40 year males, suggesting that this group is at an increased risk of developing CAD leading to young infarcts. Combination lifestyle therapies i.e., enhanced physical activity and dietary modification and therapeutic intervention would help us in the treatment and management of dyslipidemia.
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