Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Diphtheria01:28

Diphtheria

Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...
Bacterial Toxins01:12

Bacterial Toxins

Bacterial toxins are sophisticated virulence factors that enable pathogenic bacteria to interact with, invade, and damage host tissues. These toxins fall broadly into two types: protein exotoxins, which are secreted into the environment and target specific host receptors, and lipopolysaccharide endotoxins, which are structural components of the bacterial outer membrane released primarily during bacterial lysis or membrane shedding. Exotoxins generally act more selectively, binding to cell...
Receptor-mediated Endocytosis01:20

Receptor-mediated Endocytosis

Receptor-mediated endocytosis is when bulk amounts of specific molecules are imported into a cell after binding to cell surface receptors. The molecules bound to these receptors are taken into the cell through inward folding of the cell surface membrane, which is eventually pinched off into a vesicle within the cell. Structural proteins, such as clathrin, coat the budding vesicle.
Clathrin-Mediated Endocytosis of LDL
One well-characterized example of receptor-mediated endocytosis is the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Beneficial Effect of Low Dose Aspirin in Adult Patients with COVID-19: A Retrospective Observational Study in Bangladesh.

Mymensingh medical journal : MMJ·2022
Same author

Sero-prevalence of toxoplasmosis among pregnant women attending an ante-natal clinic at a teaching hospital in Al Kharj, Saudi Arabia.

Tropical biomedicine·2021
Same author

Comparison of nebulised dexmedetomidine, ketamine, or midazolam for premedication in preschool children undergoing bone marrow biopsy.

British journal of anaesthesia·2018
Same author

Comparative yielding of BACTEC MGIT 960 and GeneXpert MTB/RIF Assay for Rapid Diagnosis of Drug Resistance Tuberculosis from Sputum Specimen.

Mymensingh medical journal : MMJ·2017
Same author

Ramadan Perspective Epidemiology and Education in Diabetes (RAPEED) Study.

Mymensingh medical journal : MMJ·2017
Same author

The accuracy and cost-effectiveness of hepatitis C core antigen assay in the monitoring of anti-viral therapy in patients with chronic hepatitis C genotype 4.

Alimentary pharmacology & therapeutics·2015
Same journal

Anti-inflammatory and antipyretic properties of Kang 601 heji, a traditional Chinese oral liquid dosage form.

Asian Pacific journal of tropical biomedicine·2020
Same journal

Laboratory biosafety for handling emerging viruses.

Asian Pacific journal of tropical biomedicine·2020
Same journal

Optimal control application to an Ebola model.

Asian Pacific journal of tropical biomedicine·2020
Same journal

The anti-tubercular activity of <i>Melia azedarach</i> L. and <i>Lobelia chinensis</i> Lour. and their potential as effective anti-<i>Mycobacterium tuberculosis</i> candidate agents.

Asian Pacific journal of tropical biomedicine·2020
Same journal

Evaluation of antiviral and cytotoxic activities of methanolic extract of <i>S. grandiflora</i> (Fabaceae) flowers.

Asian Pacific journal of tropical biomedicine·2020
Same journal

Retraction notice to "Antimicrobial secondary metabolites from marine gastropod egg capsules and egg masses".

Asian Pacific journal of tropical biomedicine·2015
See all related articles

Related Experiment Video

Updated: May 12, 2026

'Bioluminescent' Reporter Phage for the Detection of Category A Bacterial Pathogens
11:31

'Bioluminescent' Reporter Phage for the Detection of Category A Bacterial Pathogens

Published on: July 8, 2011

Anthrax: an update.

S M Kamal1, A K M M Rashid, M A Bakar

  • 1Department of Medicine, Khulna Medical College, Khulna.

Asian Pacific Journal of Tropical Biomedicine
|April 10, 2013
PubMed
Summary
This summary is machine-generated.

Anthrax, a deadly zoonotic disease from Bacillus anthracis, presents in cutaneous, gastrointestinal, and inhalational forms. Effective treatments include antibiotics and vaccines, with combinations showing high survival rates.

Keywords:
AnthraxBacillus anthracisContagious diseaseCutaneous anthraxGastrointestinal anthraxHuman anthraxInhalational anthraxZoonotic disease

More Related Videos

Recombinant Protein Expression, Crystallization, and Biophysical Studies of a Bacillus-conserved Nucleotide Pyrophosphorylase, BcMazG
12:23

Recombinant Protein Expression, Crystallization, and Biophysical Studies of a Bacillus-conserved Nucleotide Pyrophosphorylase, BcMazG

Published on: May 16, 2017

Opsono-Adherence Assay to Evaluate Functional Antibodies in Vaccine Development Against Bacillus anthracis and Other Encapsulated Pathogens
13:47

Opsono-Adherence Assay to Evaluate Functional Antibodies in Vaccine Development Against Bacillus anthracis and Other Encapsulated Pathogens

Published on: May 19, 2020

Related Experiment Videos

Last Updated: May 12, 2026

'Bioluminescent' Reporter Phage for the Detection of Category A Bacterial Pathogens
11:31

'Bioluminescent' Reporter Phage for the Detection of Category A Bacterial Pathogens

Published on: July 8, 2011

Recombinant Protein Expression, Crystallization, and Biophysical Studies of a Bacillus-conserved Nucleotide Pyrophosphorylase, BcMazG
12:23

Recombinant Protein Expression, Crystallization, and Biophysical Studies of a Bacillus-conserved Nucleotide Pyrophosphorylase, BcMazG

Published on: May 16, 2017

Opsono-Adherence Assay to Evaluate Functional Antibodies in Vaccine Development Against Bacillus anthracis and Other Encapsulated Pathogens
13:47

Opsono-Adherence Assay to Evaluate Functional Antibodies in Vaccine Development Against Bacillus anthracis and Other Encapsulated Pathogens

Published on: May 19, 2020

Area of Science:

  • Veterinary Medicine
  • Infectious Diseases
  • Public Health

Background:

  • Anthrax is a severe zoonotic disease caused by Bacillus anthracis, primarily affecting herbivores.
  • Humans contract anthrax through contact with infected animals or their products, with historical epidemics and sporadic outbreaks documented worldwide.
  • While incidence has decreased in developed nations due to vaccination and improved hygiene, anthrax remains a global concern, particularly its inhalational form as a potential biowarfare agent.

Purpose of the Study:

  • To provide a comprehensive overview of anthrax, including its etiology, transmission, clinical manifestations, and historical significance.
  • To detail the various clinical forms of human anthrax: cutaneous, gastrointestinal, and inhalational.
  • To review effective antimicrobial treatments, recommended therapy durations, and available vaccines for anthrax.

Main Methods:

  • Literature review of anthrax epidemiology, clinical presentations, and treatment modalities.
  • Analysis of historical anthrax outbreaks and their impact.
  • Summary of current therapeutic strategies, including antimicrobial agents and vaccination protocols.

Main Results:

  • Human anthrax manifests primarily as cutaneous (95%) and inhalational (5%) forms, with gastrointestinal anthrax being rare (<1%).
  • Numerous antimicrobials, including penicillin, ciprofloxacin, doxycycline, and vancomycin, are effective, with a recommended 60-day therapy course.
  • Vaccination and combined therapies, such as anti-protective antigen (PA) antibody with ciprofloxacin or anthrax vaccine adsorbed (AVA) with dalbavancin, demonstrate high survival rates (90%-100%).

Conclusions:

  • Anthrax remains a significant global health threat requiring ongoing vigilance and effective control measures.
  • Prompt diagnosis and appropriate antimicrobial therapy, alongside vaccination, are crucial for managing anthrax infections.
  • Advancements in treatment, including combination therapies and vaccines, have significantly improved patient outcomes and survival rates.