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Murine Ileocolic Bowel Resection with Primary Anastomosis

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Management of opioid-induced bowel dysfunction.

Michael H Levy¹

¹Fox Chase Cancer Center, 7701 Burholme Avenue, Philadelphia PA 19111-2412, USA. mh_levy@fccc.edu

Journal of the National Comprehensive Cancer Network : JNCCN

|April 11, 2013

Summary

Opioid-induced bowel dysfunction (OIBD) is a common oncology complication. Aggressive management, including preventative laxatives and stool softeners, is crucial for patients on opioid therapy.

Area of Science:

Oncology
Gastroenterology
Palliative Care

Background:

Opioid-induced bowel dysfunction (OIBD) is a significant challenge in cancer care.
Effective management of OIBD is essential for patient comfort and treatment adherence.

Purpose of the Study:

To outline an aggressive management strategy for opioid-induced bowel dysfunction in oncology patients.
To emphasize the importance of proactive and preventative measures.

Main Methods:

Initiate bowel regimen with senna and a stool softener upon starting opioid therapy.
Rapidly titrate laxatives if initial doses are ineffective.
Add agents like bisacodyl at the first sign of constipation.
Consider fecal impaction and its associated symptoms.

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Main Results:

Proactive and aggressive management can prevent severe constipation and fecal impaction.
Timely intervention with appropriate agents is key to successful OIBD management.
Recognizing symptoms of fecal impaction is critical to avoid complications.

Conclusions:

Opioid-induced bowel dysfunction requires an aggressive, preventative approach in oncology.
Patient education on OIBD management is paramount.
"Remember the bowels" is a critical principle in palliative and oncology care.