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Related Experiment Video

Updated: May 12, 2026

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
07:01

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma

Published on: April 17, 2013

Non-Alpine thyroid angiosarcoma.

Pedro Gouveia1, Catarina Silva, Fátima Magalhães

  • 1Unidade Local de Saúde de Matosinhos, Matosinhos, Portugal.

International Journal of Surgery Case Reports
|April 11, 2013
PubMed
Summary
This summary is machine-generated.

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Thyroid angiosarcoma is a rare, aggressive cancer, often misdiagnosed. This case highlights the challenges in diagnosing and treating this non-Alpine variant, emphasizing the need for better diagnostic criteria and treatment strategies.

Area of Science:

  • Oncology
  • Pathology

Background:

  • Angiosarcoma is a rare, aggressive soft tissue neoplasm.
  • Thyroid angiosarcoma is typically found in Alpine regions, comprising 2-10% of malignant thyroid tumors there.
  • This case presents an exceptionally rare instance of thyroid angiosarcoma in a non-Alpine area.

Purpose of the Study:

  • To report a case of non-Alpine thyroid angiosarcoma.
  • To highlight diagnostic and therapeutic challenges associated with this rare malignancy.

Main Methods:

  • Case report of a 71-year-old female with a rapidly growing neck mass.
  • Surgical intervention including total thyroidectomy and resection of an esophageal implant.
  • Post-operative management and outcome assessment.

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Last Updated: May 12, 2026

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Spontaneous Murine Model of Anaplastic Thyroid Cancer
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Spontaneous Murine Model of Anaplastic Thyroid Cancer

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Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

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Main Results:

  • A 15cm mass invading adjacent tissues was identified.
  • Fine needle aspiration cytology misdiagnosed the tumor as carcinoma.
  • The patient experienced post-operative respiratory failure and died from hemoptysis due to mediastinal metastasis.

Conclusions:

  • Distinguishing thyroid angiosarcoma from anaplastic carcinoma is difficult, with similar prognoses.
  • Phenotypical features of endothelial differentiation are key in diagnosis.
  • Optimal treatment strategies for thyroid angiosarcoma remain unclear due to its rarity and poor prognosis.