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Retrospection to discovery of bursal function and recognition of avian dendritic cells; past and present

Imre Oláh1, Nándor Nagy

  • 1Department of Human Morphology and Developmental Biology, Faculty of Medicine, Semmelweis University, Hungary. olah.imre@med.semmelweis-univ.hu

Developmental and Comparative Immunology
|April 11, 2013
PubMed

In 1954 the discovery of bursal function was one of the major contributions to the formation of the T and B cell concept of immunology. In 1978 the avian dendritic cells; bursal secretory dendritic cell (BSDC) and follicular dendritic cell (FDC) in the cecal tonsil were recognized. In 1982 the interdigitating dendritic cell was described in the periarteriolar lymphatic sheath (PALS) of the spleen. This paper is a retrospection of the stories of the discovery of bursal function and recognition of avian dendritic cells and includes the markers which can be used for monitoring and characterizing avian dendritic cells.

Keywords:
Avian dendritic cellsBursal function by Bruce GlickDevelopment and differentiation of BSDC and FDCLangerhans cells in esophagus and skin

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