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New dimeric and trimeric coumarin glucosides from Daphne retusa Hemsl
Farrukh Mansoor1, Itrat Anis1, Sajjad Ali2
1Department of Chemistry, University of Karachi, Karachi, 75270, Pakistan.
Fitoterapia
|April 11, 2013
Abstract:
New dimeric and a trimeric coumarin glucosides namely Daphneretusin A (1) Daphneretusin B (2) along with three known oligomers (3-5) were obtained as a result of bioassay guided fractionation of Daphne retusa Hemsl. Fractions (n-hexane, CHCl3, AcOEt, CH3OH and water) exhibited potent radical scavenging activity in relevant non-physiological bioassays. The structures of isolated compounds were elucidated by UV, IR, EIMS, FAB-MS, 1D, and 2D NMR spectroscopic analysis.
