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Related Experiment Videos

Recent experience with diaphragmatic hernia and ECMO.

C G Howell1, R M Hatley, R F Boedy

  • 1Department of Surgery, Medical College of Georgia Children's Medical Center, Augusta 30912-4070.

Annals of Surgery
|June 1, 1990
PubMed
Summary
This summary is machine-generated.

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Extracorporeal membrane oxygenation (ECMO) significantly improves survival rates for infants with diaphragmatic hernia. Early referral to ECMO centers is crucial for infants undergoing surgical repair, especially when ECMO is not readily available.

Area of Science:

  • Neonatalogy
  • Pediatric Surgery
  • Cardiopulmonary Support

Background:

  • Diaphragmatic hernia is a critical congenital condition requiring complex management.
  • Extracorporeal membrane oxygenation (ECMO) offers life support for neonates with severe respiratory failure.

Purpose of the Study:

  • To evaluate the impact of ECMO on survival rates in infants with diaphragmatic hernia.
  • To assess the outcomes of infants with diaphragmatic hernia managed with and without ECMO.

Main Methods:

  • Retrospective analysis of 74 infants treated with ECMO over 4 years.
  • Specific focus on 27 infants with diaphragmatic hernia, comparing those who received ECMO post-surgery with those who did not.

Main Results:

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  • Overall ECMO survival was 84% (62/74).
  • For diaphragmatic hernia, 7 of 11 infants (64%) survived with ECMO post-surgery.
  • Eight infants died before ECMO initiation, representing potential candidates who might have survived.

    • Conclusions:

    • ECMO, when indicated after diaphragmatic hernia repair, improves oxygen delivery and survival.
    • Early referral to ECMO centers is recommended for infants with diaphragmatic hernia awaiting or recovering from surgery.
    • Delivery at centers with integrated surgical and ECMO expertise is advised for prenatal diagnoses.