Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
Cancer02:18

Cancer

Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Cancer-Critical Genes I: Proto-oncogenes01:33

Cancer-Critical Genes I: Proto-oncogenes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparative Efficacy of Non-opioid Analgesic Drugs for Chronic Cancer Pain: A Bayesian Network Meta-analysis.

Drugs·2026
Same author

Oropharyngeal Dysphagia as a Metabolic Emergency: A Comprehensive Review on Nutritional Barriers, Sarcopenia, and Management Strategies.

Nutrients·2026
Same author

The healing promise of narrative medicine in cancer care.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer·2026
Same author

Management of Nonmedical Use of Prescribed Pharmaceutical Fentanyl Products in an Acute Palliative Care Unit: A Case Series.

Journal of palliative medicine·2026
Same author

Age differences in symptom burden of patients with advanced cancer admitted to an acute palliative care unit.

Internal and emergency medicine·2026
Same author

Comprehensive Palliative Care in Patients with Lung Cancer Admitted to an Acute Palliative Care Unit.

Cancers·2026

Related Experiment Video

Updated: May 12, 2026

A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery
07:14

A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery

Published on: January 18, 2018

Cancer pain.

Sebastiano Mercadante1

  • 1Anesthesia and Intensive Care Unit and Pain Relief and Palliative Care Unit, La Maddalena Cancer Center, Palermo, Italy. terapideldolore@lamaddalenanet.it

Current Opinion in Supportive and Palliative Care
|April 11, 2013
PubMed
Summary

Recent advancements in cancer pain management offer new therapeutic strategies. Research highlights include factors influencing pain relief, managing breakthrough pain, and the role of pharmacogenetics in treatment.

Area of Science:

  • Oncology
  • Pain Management
  • Pharmacology

Background:

  • Cancer pain management is evolving with new research.
  • Updated data may influence current therapeutic approaches and clinical guidelines.

Purpose of the Study:

  • To review recent innovations and data in cancer pain management.
  • To highlight key research areas impacting treatment strategies.

Main Methods:

  • Literature review of current research in cancer pain.
  • Synthesis of findings related to analgesic response, breakthrough pain, opioid switching, and pharmacogenetics.

Main Results:

  • Identified key factors influencing analgesic response in cancer patients.
  • Summarized findings on managing breakthrough cancer pain.

Related Experiment Videos

Last Updated: May 12, 2026

A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery
07:14

A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery

Published on: January 18, 2018

  • Reviewed data on opioid switching and the impact of pharmacogenetics on treatment efficacy.
  • Conclusions:

    • Emerging data suggests potential shifts in cancer pain management.
    • Further studies are needed to validate these findings and refine guidelines.