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Related Concept Videos

Neurulation01:30

Neurulation

Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the anterior...
Vertebral Column: Regions and Curvature01:16

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The vertebral column or spine is a flexible column that supports the head, neck, and body and  allows for their movements. It also protects the spinal cord.
Regions of the Vertebral Column
In an adult, the spine is subdivided into five regions: the cervical, the thoracic, the lumbar, the sacral, and the coccygeal region. The spine initially develops as a series of 33 vertebrae; after 20 years of age, the nine bones in the sacral region, five sacral, and four coccygeal bones fuse to form the...
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Spinal Cord: Cross-sectional Anatomy

The cross-sectional anatomy of the spinal cord offers a detailed view of its complex structure and function within the central nervous system. At the core of the spinal cord lies the gray matter, characterized by its butterfly or "H"-shaped appearance in cross-section. This central region is enveloped by white matter, with the overall structure divided into symmetrical halves by the dorsal median sulcus and the ventral median fissure.
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The spinal cord, a critical component of the central nervous system, extends from the base of the brainstem to the lumbar region of the vertebral column. It is essential for maintaining physical stability and facilitating communication between the brain and peripheral parts of the body.
Spinal Cord: Gross Anatomy01:15

Spinal Cord: Gross Anatomy

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Updated: May 12, 2026

Surgical Approach and Complications of Stand-alone Lateral Trans-Psoas Interbody Fusion
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Surgical Approach and Complications of Stand-alone Lateral Trans-Psoas Interbody Fusion

Published on: February 14, 2025

Spina bifida grown up.

Gregory S Liptak1, Kimberlee Garver, Nienke P Dosa

  • 1Department of Pediatrics, Golisano Children's Hospital, Upstate Medical University, Syracuse, NY 13210, USA.

Journal of Developmental and Behavioral Pediatrics : JDBP
|April 11, 2013
PubMed
Summary

Most adults with spina bifida require ongoing medical care, including screenings for common diseases and management of condition-specific complications. Specialized follow-up is crucial for optimal health outcomes.

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Area of Science:

  • Neurology
  • Urology
  • Public Health

Background:

  • The demographic of individuals with spina bifida has shifted, with the majority now being adults.
  • This necessitates a transition in healthcare focus from pediatric to adult-centered management.

Purpose of the Study:

  • To outline essential components of healthcare delivery for adults with spina bifida.
  • To highlight common health conditions and spina bifida-related complications requiring surveillance and management.

Main Methods:

  • This is a review and synthesis of current knowledge regarding adult spina bifida care.
  • Recommendations are based on established medical guidelines and clinical expertise.

Main Results:

  • Adults with spina bifida require routine screening for hypertension, hyperlipidemia, and cancer.
  • Management should address spina bifida complications: pressure sores, lymphedema, sexual dysfunction, infertility, and hydrocephalus.
  • Chiari-related symptoms like sleep apnea and urologic/renal dysfunction are common and require attention.

Conclusions:

  • Comprehensive adult spina bifida care necessitates regular specialist follow-up (urology, neurosurgery, physiatry).
  • Healthcare providers must recognize the impact of executive dysfunction and nonverbal learning disabilities on self-management, independence, and employment.