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Thermosensation

Thermosensation

Peripheral thermosensation is the perception of external temperature. A change in temperature (on the surface of the skin and other tissues) is detected by a family of temperature-sensitive ion channels called Transient Receptor Potential, or TRP, receptors. These receptors are located on free nerve endings. Those detecting cold temperatures are closer to the surface of the skin than the nerve endings detecting warmth. These thermoTRP channels, while temperature selective, have relatively...

Membrane Fluidity

Membrane Fluidity

Cell membranes are composed of phospholipids, proteins, and carbohydrates loosely attached to one another through chemical interactions. Molecules are generally able to move about in the plane of the membrane, giving the membrane its flexible nature called fluidity. Two other features of the membrane contribute to membrane fluidity: the chemical structure of the phospholipids and the presence of cholesterol in the membrane.

Membrane Fluidity

Membrane Fluidity

Membrane fluidity is explained by the fluid mosaic model of the cell membrane, which describes the plasma membrane structure as a mosaic of components—including phospholipids, cholesterol, proteins, and carbohydrates—that gives the membrane a fluid character.
Mosaic nature of the membrane
The mosaic characteristic of the membrane helps the plasma membrane remain fluid. The integral proteins and lipids exist as separate but loosely-attached molecules in the membrane. The membrane is a relatively...

Factors Affecting Perception

Factors Affecting Perception

Perception is influenced by perceptual set, context, motivation, and emotion. Perceptual set, or perceptual expectancy, refers to the tendency to perceive things in a particular way, influenced by previous experiences and expectations. This phenomenon affects the interpretation of stimuli, creating a set of mental tendencies and assumptions that impact sensory perceptions of sound, taste, touch, and sight.
An illustrative example of a perceptual set is the scenario where an airline pilot told...

Assessing Body Temperature - Tympanic membrane

Assessing Body Temperature - Tympanic membrane

Assessing tympanic membrane temperature involves using a tympanic membrane thermometer (TMT). Here is a step-by-step guide:
Step 1: Begin by practicing good hand hygiene to prevent the transmission of microorganisms.
Step 2: Turn on the thermometer and wait until the ready sign appears on the screen to ensure accurate measurement.
Step 3: Slide the probe cover in place to prevent cross-contamination.
Step 4: Instruct the patient to tilt their head to the side for comfort and check for cerumen...

Potentiometry: Membrane Electrodes

Potentiometry: Membrane Electrodes

Membrane electrodes, also known as p-ion electrodes, use membranes that selectively interact with free analyte ions, generating a potential difference across the membrane. The resulting membrane potential, known as the asymmetry potential, is not zero even when analyte concentrations on both sides of the membrane are equal. The membrane's response is typically not selective to a single analyte but proportional to the concentration of all ions in the sample solution capable of interacting at the...

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Related Experiment Video

Updated: May 12, 2026

Temperature-Controlled Assembly and Characterization of a Droplet Interface Bilayer

Temperature-Controlled Assembly and Characterization of a Droplet Interface Bilayer

Published on: April 19, 2021

Prospectives on membrane perceptions of temperature.

Prasanna Mohanty¹

¹INSA Honorary Scientist, Functional Ecology at RPRC, Bhubaneswar, 751 015 India ; DAVV, Indore, 452 001 India.

Physiology and Molecular Biology of Plants : an International Journal of Functional Plant Biology

|April 11, 2013

Summary

Temperature significantly impacts biological processes and energetics. This note explores potential mechanisms for how organisms sense and respond to temperature changes, drawing on existing research.

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Last Updated: May 12, 2026

Temperature-Controlled Assembly and Characterization of a Droplet Interface Bilayer

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Purification and Reconstitution of TRPV1 for Spectroscopic Analysis

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Area of Science:

Thermodynamics
Biophysics
Molecular Biology

Background:

Temperature is a fundamental factor influencing energetics and biological system functions.
While thermodynamics (enthalpy, entropy) explains temperature's energetic role, specific biological temperature sensing mechanisms remain elusive.

Purpose of the Study:

To discuss the potential mechanisms of biological temperature sensing.
To review existing studies and trends related to temperature perception in organisms.

Main Methods:

Literature review of studies on temperature effects in biological systems.
Analysis of trends in biophysical and molecular biology research concerning thermosensation.

Main Results:

Biological systems are quantitatively affected by temperature across various processes.
Identifying precise molecular or cellular mechanisms for temperature sensing presents a significant challenge.

Conclusions:

Further research is needed to elucidate the specific pathways and molecules involved in biological temperature sensing.
Understanding thermosensation is crucial for comprehending life's energetic and functional responses to environmental temperature shifts.