Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...

Venous Thrombosis III: Interprofessional Care

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...

Peripheral Artery Disease V: Postoperative Nursing Management

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...

Peripheral Artery Disease I: Introduction

Peripheral Artery Disease I: Introduction

Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

De Novo Atherosclerotic Renal Artery Stenosis Covered Stent Treatment for Resistant Hypertension (ARTISAN) Results.

Journal of the Society for Cardiovascular Angiography & Interventions·2025

Same author

Rationale and design of the DEFIANCE study: A randomized controlled trial of mechanical thrombectomy versus anticoagulation alone for iliofemoral deep vein thrombosis.

American heart journal·2024

Same author

Incidence of Mortality and Complications in High-Risk Pulmonary Embolism: A Systematic Review and Meta-Analysis.

Journal of the Society for Cardiovascular Angiography & Interventions·2024

Same author

Five-Year Safety and Effectiveness of Paclitaxel Drug-Coated Balloons Alone or With Provisional Bare Metal Stenting for Real-World Femoropopliteal Lesions: IN.PACT Global Study Subgroup Analysis.

Circulation. Cardiovascular interventions·2024

Same author

Outcomes in High-Risk Pulmonary Embolism Patients Undergoing FlowTriever Mechanical Thrombectomy or Other Contemporary Therapies: Results From the FLAME Study.

Circulation. Cardiovascular interventions·2023

Same author

Randomized controlled trial of mechanical thrombectomy vs catheter-directed thrombolysis for acute hemodynamically stable pulmonary embolism: Rationale and design of the PEERLESS study.

American heart journal·2023

Search research articles

Related Experiment Video

Updated: May 12, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

Mechanical thrombectomy in peripheral arterial interventions.

Gary M Ansel¹, Charles F Botti, Mitchell J Silver

¹MidWest Cardiology Research Foundation, MidOhio Cardiology and Vascular Consultants, Riverside Methodist Hospital, 3705 Olentangy River Road, Columbus, OH 43214, USA. Gansel@MOCVC.com

The Journal of Invasive Cardiology

|April 12, 2013

Summary

This summary is machine-generated.

Acute arterial closure is a serious condition. Mechanical thrombectomy offers a less invasive, effective treatment for acute limb ischemia, reducing amputation and death risks when combined with other endovascular devices.

Related Experiment Videos

Last Updated: May 12, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

Area of Science:

Vascular Surgery
Interventional Cardiology
Endovascular Therapy

Background:

Acute arterial closure from thrombosis or embolization poses significant life-threatening risks.
Traditional surgical interventions like bypass and embolectomy have limitations including high morbidity and mortality.
Percutaneous thrombolysis, while less invasive, is associated with bleeding risks and delayed blood flow restoration.

Purpose of the Study:

To evaluate the efficacy of mechanical thrombectomy, specifically rheolytic thrombectomy, as a primary treatment for acute limb ischemia.
To assess the benefits of combining mechanical thrombectomy with other endovascular devices for treating arterial occlusions.
To determine the safety and effectiveness of minimally invasive endovascular approaches in managing acute arterial closure.

Main Methods:

Rheolytic thrombectomy as a key mechanical thrombectomy technique.
Utilization of complementary endovascular devices alongside mechanical thrombectomy.
Percutaneous treatment strategies for acute arterial occlusion.

Main Results:

Mechanical thrombectomy, particularly rheolytic thrombectomy, has matured into a viable therapy for acute limb ischemia.
The combination of experienced operators, mechanical thrombectomy, and adjunctive endovascular devices enables successful treatment.
This integrated approach significantly reduces the risk of amputation and mortality in patients with acute limb ischemia.

Conclusions:

Mechanical thrombectomy represents a significant advancement in treating acute arterial closure.
Minimally invasive endovascular techniques, including rheolytic thrombectomy, offer a less risky alternative to traditional surgery.
Experienced operators can achieve successful outcomes for acute limb ischemia with low amputation and death rates using these modern therapies.