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Published on: June 4, 2021
Mechanical thrombectomy in deep venous thrombosis.
Ruth L Bush1, Peter H Lin, Alan B Lumsden
1Division of Vascular Surgery and Endovascular Therapy, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston VAMC - 2002 Holcomb Blvd (112), Houston, TX 77030, USA. rbush@bcm.tmc.edu
Deep venous thrombosis (DVT) can cause serious complications. Percutaneous mechanical thrombectomy offers a safe and effective endovascular treatment to remove thrombus burden and potentially preserve venous valve function.
Area of Science:
- Vascular Surgery
- Interventional Radiology
- Cardiovascular Medicine
Background:
- Deep venous thrombosis (DVT) can lead to acute limb symptoms, chronic post-phlebitic syndrome, pulmonary embolism, and death.
- Current anticoagulation therapies manage clot propagation but do not reduce existing thrombus burden.
- Delayed DVT complications stem from valvular damage and scarring caused by chronic thrombus.
Purpose of the Study:
- To explore the efficacy and safety of percutaneous mechanical thrombectomy for treating venous thrombotic disease.
- To highlight the potential of endovascular approaches in relieving thrombus burden.
- To discuss the simultaneous treatment of underlying anatomic lesions and preservation of venous valve function.
Main Methods:
- Review of endovascular management strategies for venous thrombotic disease.
- Focus on percutaneous mechanical thrombectomy, alone or combined with pharmacological thrombolysis.
- Discussion of treatment outcomes including thrombus burden relief and valve function.
Main Results:
- Percutaneous mechanical thrombectomy is demonstrated as a safe and effective method for thrombus removal in DVT.
- This endovascular approach can relieve thrombus burden, potentially preserving venous valve function.
- Simultaneous treatment of inciting anatomic lesions is feasible during the procedure.
Conclusions:
- Percutaneous mechanical thrombectomy is a valuable endovascular option for managing venous thrombotic disease.
- It offers advantages over conventional therapy by actively reducing thrombus burden.
- This technique holds promise for improving outcomes and preventing long-term sequelae of DVT.
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