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Related Concept Videos

DNA Microarrays02:34

DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...
Genomics02:02

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...

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Related Experiment Video

Updated: May 12, 2026

DNA Microarrays: Sample Quality Control, Array Hybridization and Scanning
09:27

DNA Microarrays: Sample Quality Control, Array Hybridization and Scanning

Published on: March 15, 2011

Genomic microarrays in the spotlight.

Kiran K Mantripragada1, Patrick G Buckley, Teresita Diaz de Ståhl

  • 1Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, 751 85 Uppsala, Sweden.

Drug Discovery Today
|April 12, 2013
PubMed
Summary

Genomic microarrays enable high-resolution DNA copy number aberration detection. This technology offers advanced applications in research, diagnostics, and gene annotation for future genetic analysis.

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Last Updated: May 12, 2026

DNA Microarrays: Sample Quality Control, Array Hybridization and Scanning
09:27

DNA Microarrays: Sample Quality Control, Array Hybridization and Scanning

Published on: March 15, 2011

Global Gene Expression Analysis Using a Zebrafish Oligonucleotide Microarray Platform
13:14

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16:37

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Area of Science:

  • Genomics
  • Molecular Biology

Background:

  • Microarray-based comparative genomic hybridization (array-CGH) provides high-resolution DNA copy number aberration detection.
  • Genomic microarrays are increasingly vital tools in genetic analysis.

Purpose of the Study:

  • To outline the use and limitations of various targets for genomic microarray construction.
  • To discuss applications and future aspects of genomic microarrays in research and diagnostics, epigenetic profiling, and gene annotation.

Main Methods:

  • Utilizing genomic clones, cDNA clones, and PCR products as targets for genomic microarray construction.
  • Reviewing current and future applications of genomic microarrays.

Main Results:

  • Genomic microarrays offer high-resolution detection of DNA copy number aberrations.
  • Various targets, including genomic clones, cDNA clones, and PCR products, can be used for microarray construction.

Conclusions:

  • Genomic microarrays represent a new generation of high-resolution, high-throughput genetic analysis tools.
  • These arrays have broad applications in research, diagnostics, epigenetic profiling, and gene annotation.