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Childhood allergies affect health-related quality of life
Corina Covaciu1, Anna Bergström, Tomas Lind
1Centre for Occupational and Environmental Medicine, Stockholm County Council, Stockholm, Sweden. corina.covaciu@sll.se
Insights
Allergic diseases, especially asthma, significantly impact children's quality of life. Asthma symptom control is crucial for improving health-related quality of life (HRQoL) in pediatric populations.
Area of Science:
- Pediatric Allergy and Immunology
- Quality of Life Research
- Public Health
Background:
- Most studies examine single allergic conditions and disease-specific quality of life measures.
- A comprehensive understanding of how various childhood allergies affect overall well-being is lacking.
Purpose of the Study:
- To comparatively assess the impact of asthma, rhinitis, eczema, and food hypersensitivity on health-related quality of life (HRQoL) in Swedish 8-year-olds.
- To analyze the influence of specific allergic conditions on a general HRQoL instrument.
Main Methods:
- Utilized data from the Swedish BAMSE birth cohort.
- Collected HRQoL data using the EQ-5D instrument from parents of 3236 children at age 8.
- Gathered information on allergic symptoms, sensitization, and lung function.
Main Results:
- Children with allergic diseases reported lower EQ visual analog scale (VAS) scores compared to healthy children.
- Asthma was associated with the lowest median EQ VAS (90) and highest "pain or discomfort" prevalence (18.2%).
- Frequent and effort-induced wheezing correlated with increased "anxiety or depression" (23.3% and 15.4%).
Conclusions:
- Swedish 8-year-olds generally have good HRQoL, but allergic diseases significantly diminish it, particularly asthma.
- Asthma symptoms are key factors affecting pediatric HRQoL.
- Effective asthma symptom management is essential for enhancing children's quality of life.
Objective:
The majority of studies investigating the effects of allergy on the children's health-related quality of life (HRQoL) address one particular allergic disease, using a disease-specific HRQoL instrument. This work aims to assess the comparative impact on HRQoL of several allergic conditions of childhood (asthma, rhinitis, eczema, and food hypersensitivity) in a large, population-based sample of Swedish 8-year-olds.
Methods:
Data were obtained from a Swedish birth cohort (BAMSE). At the 8-year follow-up, parents of 3236 children completed the standardized generic HRQoL instrument EQ-5D and reported on the children's symptoms of asthma, rhinitis, eczema, and food hypersensitivity. Information on allergic sensitization and lung function was available for a sub-sample of the children (n = 2370 and 2425, respectively).
Results:
Children in the study population had a median EQ visual analog scale (VAS) of 98 (Inter Quartile Range, IQR, 90-100). The median EQ VAS was significantly lower in children with allergic diseases. Children with asthma had the lowest median EQ VAS (90, IQR 85-98) and reported the highest prevalence of problems of "pain or discomfort" (18.2%, compared to 5.5% in children without asthma). Frequent wheezing and effort-induced wheezing were associated with high prevalence of problems of "anxiety or depression" (23.3% and 15.4%, respectively).
Conclusions:
Swedish 8-year-olds enjoy a good HRQoL, which though is significantly impacted by allergic diseases and particularly by asthma. Asthma symptoms are important determinants of HRQoL and symptom control should be a major goal in asthma management.
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