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Updated: May 12, 2026

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
Published on: February 6, 2020
Self-assembly of bridged silsesquioxanes: modulating structural evolution via cooperative covalent and noncovalent
Gaelle Creff1, Benoît P Pichon, Christophe Blanc
1Laboratoire Charles Coulomb (UMR CNRS 5521), Université Montpellier 2, Montpellier, France.
Abstract:
The self-assembly of a bis-urea phenylene-bridged silsesquioxane precursor during sol-gel synthesis has been investigated by in situ infrared spectroscopy, optical microscopy, and light scattering. In particular, the evolution of the system as a function of processing time was correlated with covalent interactions associated with increasing polycondensation and noncovalent interactions such as hydrogen bonding. A comprehensive mechanism based on the hydrolysis of the phenylene-bridged organosilane precursor prior to the crystallization of the corresponding bridged silsesquioxane via H-bonding and subsequent irreversible polycondensation is proposed.
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