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Related Concept Videos

Probiotics01:22

Probiotics

Probiotics are live, non-pathogenic microorganisms that confer health benefits by modulating the gut microbiota. The human gastrointestinal tract harbors a complex microbial ecosystem, and the balance of this microbiota is crucial for digestive and systemic health. Among the most extensively studied and utilized probiotics are species formerly classified within the genera Lactobacillus and Bifidobacterium. These organisms not only naturally colonize the human gut but are also consumed through...
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Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
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Allergic Reactions02:06

Allergic Reactions

Overview
Allergic Drug Reactions01:27

Allergic Drug Reactions

Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing numerous...
Antiasthma Drugs: Leukotriene Modifiers01:19

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Gut-Brain Axis01:22

Gut-Brain Axis

The gut–brain axis is a bidirectional communication system that connects the gastrointestinal tract and the brain. This interaction is mediated through multiple pathways, including the vagus nerve, hormonal signals, immune responses, and chemical messengers produced by gut microbes.Microbial Contributions to Brain FunctionGut microbiota contributes significantly to brain function by producing neuroactive compounds. These include neuroactive compounds that influence neurotransmitters such as...

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Investigating the Effects of Probiotics on Pneumococcal Colonization Using an In Vitro Adherence Assay
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Published on: April 28, 2014

Probiotic effects in allergic disease.

Intan H Ismail1, Paul V Licciardi, Mimi Lk Tang

  • 1Allergy and Immune Disorders, Murdoch Childrens Research Institute, Melbourne, Victoria, Australia; Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia; Department of Paediatrics, Universiti Putra Malaysia, Kuala Lumpur, Malaysia.

Journal of Paediatrics and Child Health
|April 12, 2013
PubMed
Summary
This summary is machine-generated.

Probiotics show promise for preventing eczema in early childhood, particularly when given pre-natally. More research is needed to confirm their effectiveness in treating existing allergic diseases.

Keywords:
allergic diseaseimmune functionintestinal microbiotaprebioticprobiotic

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Area of Science:

  • Immunology and Microbiology
  • Pediatric Allergy and Dermatology

Background:

  • Rising rates of allergic diseases correlate with decreased early-life microbial exposure.
  • Probiotics are increasingly considered for managing and preventing allergic conditions.

Purpose of the Study:

  • To review recent clinical studies on the use of probiotics for allergic disease prevention and treatment.
  • To assess the efficacy of probiotics, alone or with prebiotics, in managing allergic conditions.

Main Methods:

  • Systematic review of recent publications focusing on clinical trials.
  • Analysis of studies involving pre-natal and post-natal probiotic administration.

Main Results:

  • Combined pre-natal and post-natal probiotic use shows potential for preventing childhood eczema.
  • The pre-natal administration of probiotics appears crucial for beneficial effects.
  • Insufficient evidence currently supports probiotic use for established allergic disease treatment, though new research is encouraging.

Conclusions:

  • Probiotics are a promising strategy for the primary prevention of allergic diseases.
  • Further well-designed intervention studies are essential to establish definitive efficacy.
  • The role of probiotics in treating established allergic conditions requires further investigation.