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Neisseria meningitidis Infection of Induced Pluripotent Stem-Cell Derived Brain Endothelial Cells
Published on: July 14, 2020
Environmental survival of Neisseria meningitidis
Y-L Tzeng1, L E Martin, D S Stephens
1Department of Medicine, Division of Infectious Diseases, Emory University, Atlanta, GA, USA.
Abstract:
Neisseria meningitidis is transmitted through the inhalation of large human respiratory droplets, but the risk from contaminated environmental surfaces is controversial. Compared to Streptococcus pneumoniae and Acinetobacter baumanni, meningococcal viability after desiccation on plastic, glass or metal surfaces decreased rapidly, but viable meningococci were present for up to 72 h. Encapsulation did not provide an advantage for meningococcal environmental survival on environmental surfaces.
Insights
Neisseria meningitidis survival on surfaces is controversial. While meningococci viability decreased rapidly compared to other bacteria, they remained viable on surfaces for up to 72 hours.
Area of Science:
- Microbiology
- Infectious Diseases
- Environmental Health
Background:
- Neisseria meningitidis transmission primarily occurs via respiratory droplets.
- The role of environmental surfaces in the spread of meningococcal disease remains unclear.
Purpose of the Study:
- To investigate the viability of Neisseria meningitidis on various environmental surfaces.
- To compare meningococcal survival rates with other common respiratory pathogens.
Main Methods:
- Assessing Neisseria meningitidis survival on plastic, glass, and metal surfaces after desiccation.
- Comparing survival rates with Streptococcus pneumoniae and Acinetobacter baumanni.
- Evaluating the impact of encapsulation on meningococcal environmental survival.
Main Results:
- Meningococcal viability decreased rapidly on tested surfaces compared to S. pneumoniae and A. baumanni.
- Viable Neisseria meningitidis were detected on surfaces for up to 72 hours.
- Encapsulation did not enhance meningococcal survival on environmental surfaces.
Conclusions:
- Environmental surfaces may play a role in Neisseria meningitidis transmission, albeit with limited viability.
- Survival time on surfaces is shorter than some other bacteria, but still significant.
- Surface contamination risk warrants further investigation in meningococcal disease epidemiology.
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