[Crocodile tears syndrome]

Area of Science:

• Neurology
• Ophthalmology

Context:

• Peripheral facial nerve paralysis affects nerve function.
• Gustatory lacrimation (crocodile tears) is a rare sequel.

Purpose:

• To investigate the occurrence and underlying mechanisms of gustatory lacrimation following facial nerve paralysis.
• To identify predictors and treatment options for this condition.

Summary:

• Gustatory lacrimation was observed in 16 out of 245 patients with peripheral facial nerve paralysis.
• The phenomenon is associated with complete or incomplete nerve degeneration, often near the geniculate ganglion.
• Early signs of reduced lacrimation can predict the onset of gustatory lacrimation.

Impact:

• Provides insights into the neuropathophysiology of facial nerve damage.
• Suggests early diagnostic indicators for gustatory lacrimation.
• Offers potential therapeutic strategies including pharmacological and surgical interventions.