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Published on: September 5, 2017

Outcomes of children treated for tuberculosis with second-line medications in Georgia, 2009-2011

M Gegia1, H E Jenkins, I Kalandadze

  • 1United States Agency for International Development Georgia TB Prevention Project, Tbilisi, Georgia.

The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease
|April 12, 2013
PubMed

Insights

Pediatric drug-resistant tuberculosis (DR-TB) in Georgia showed a 77.1% success rate with prompt treatment. This national-level study highlights achievable outcomes for children with DR-TB.

Area of Science:

  • Public Health
  • Infectious Diseases
  • Pediatrics

Background:

  • Drug-resistant tuberculosis (DR-TB) poses a significant threat in former Soviet Union countries like Georgia.
  • Limited research exists on pediatric DR-TB, particularly at a national scale.

Purpose of the Study:

  • To characterize pediatric multidrug-resistant TB (MDR-TB) cases in Georgia.
  • To evaluate treatment outcomes for pediatric MDR-TB patients in Georgia.

Main Methods:

  • Retrospective analysis of pediatric (<16 years) MDR-TB cases notified in Georgia (2009-2011).
  • Assessment of baseline characteristics, treatment details, and patient outcomes.

Main Results:

  • 45 pediatric DR-TB cases were identified between 2009-2011.
  • Median age was 7.7 years; over half had prior TB treatment.
  • Successful treatment outcomes were achieved in 77.1% of cases not still on treatment.

Conclusions:

  • This study provides national-level data on pediatric DR-TB treatment outcomes in Georgia.
  • Successful treatment outcomes are achievable in pediatric DR-TB patients.
Abstract

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