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Updated: May 12, 2026

Detecting the Lyme Disease Spirochete, Borrelia Burgdorferi, in Ticks Using Nested PCR
Published on: February 4, 2018
[Unclassified cardiomyopathy or Lyme carditis? A three year follow-up]
Marcin Konopka1, Marek Kuch, Wojciech Braksator
1Department of Cardiology, 2nd Medical Faculty, Medical University, Warsaw, Poland. marcin.konopka@op.pl
Insights
Lyme carditis, a heart complication of Lyme disease, was diagnosed in a woman presenting with cardiac symptoms. Early detection through advanced imaging and biopsy confirmed the Borrelia burgdorferi infection.
Area of Science:
- Cardiology
- Infectious Diseases
- Medical Diagnostics
Background:
- Lyme carditis is a cardiac manifestation of early disseminated Lyme disease, caused by Borrelia burgdorferi.
- Tick-borne illnesses can present with diverse and sometimes atypical symptoms, challenging diagnosis.
Observation:
- A 41-year-old woman presented with fatigue, dyspnea, supraventricular cardiac arrhythmia, and cardiomegaly.
- Transthoracic echocardiography yielded atypical results, prompting cardiac magnetic resonance imaging (CMR).
- CMR revealed structural cardiac changes and late gadolinium enhancement in the apex.
Findings:
- Endomyocardial biopsy and serology confirmed Lyme carditis.
- The patient's cardiac condition was monitored for three years post-diagnosis.
Implications:
- This case highlights the importance of considering Lyme carditis in patients with unexplained cardiac symptoms and arrhythmias.
- Advanced imaging techniques like CMR are crucial for diagnosing cardiac involvement in Lyme disease.
- Timely diagnosis and management of Lyme carditis are essential for patient outcomes.
Abstract:
Lyme carditis can be a clinical manifestation of the early disseminated stage of Lyme disease caused by the tick-transmitted pathogen Borrelia burgdorferi. We present the case of a 41 year-old Caucasian woman referred to our hospital with symptoms of fatigue, progressive exertional dyspnoea, supraventricular cardiac arrhythmia, and an enlarged heart revealed on chest radiography. Following an untypical result of transthoracic echocardiography, cardiac magnetic resonance was performed. This showed structural cardiac changes and focus of late gadolinium enhancement in the midwall of the apex region. Further diagnostic processes, including endomyocardial biopsy and serology tests, made it possible to diagnose Lyme carditis. Clinical observation was followed-up for three years.
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