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Nanoparticle Delivery of an Oligonucleotide Payload in a Glioblastoma Multiforme Animal Model
Published on: September 27, 2024
Aiming at neuroblastoma and hitting other worthy targets
1Department of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA. nina_schor@urmc.rochester.edu
Abstract:
Neuroblastoma is, at once, the most common and deadly extracranial solid tumor of childhood. Efforts aimed at targeting the neural characteristics of these tumors have taught us much about neural crest cell biology, apoptosis induction in the nervous system, and neurotrophin receptor signaling and intracellular processing. But neuroblastoma remains a formidable enemy to the oncologist and an enigmatic target to the neuroscientist.
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