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Updated: May 12, 2026

Detecting the Lyme Disease Spirochete, Borrelia Burgdorferi, in Ticks Using Nested PCR
Published on: February 4, 2018
A patient with Lyme arthritis presenting in general practice
Dirk Mosshammer1, Harald Hlobil, Stefanie Joos
1University Hospital Tübingen, Division of General Practice, Tübingen, Germany.
Lyme disease, caused by Borrelia burgdorferi bacteria, affects various organs and stages, often presenting as arthritis. Early antibiotic treatment improves the prognosis for this tick-borne illness.
Area of Science:
- Infectious Diseases
- Rheumatology
- Bacteriology
Background:
- Lyme disease, or Lyme borreliosis, is caused by Borrelia burgdorferi bacteria transmitted through tick bites.
- It can affect multiple organs and presents in distinct early and late stages.
- Manifestations range from skin lesions and facial palsy to arthritis and neurological disorders.
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