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[Pregnancy in Gaucher disease]

H Boufettal1, A Quessar2, Z Jeddaoui1

  • 1Service de gynécologie-obstétrique, faculté de médecine et de pharmacie, université Ain Chok, centre hospitalier universitaire Ibn Rochd, Casablanca, Maroc.

Journal De Gynecologie, Obstetrique Et Biologie De La Reproduction
|April 13, 2013
PubMed

Gaucher disease is a lysosomal storage disorder due to deficiency of glucocerebrosidase. The association with pregnancy exposes the worsening of the disease and complications of pregnancy and puerperium. We report a case of pregnancy in a woman of 35 years, suffering from Gaucher disease type 1. Pregnancy had a favorable outcome. Complications occurred. They were kept under control. The outcome was favorable. The authors discuss the evolution of the disease during pregnancy and management of complications. They can occur during pregnancy, post-partum and breastfeeding. Support begins with preconception consultation. It involves finding and correcting the biological problems and deficiencies, and management of complications. Genetic counseling is important, it helps prevent inbreeding.

Keywords:
AllaitementBreastfeedingConseil génétiqueCounselingGaucher diseaseGrossesseHémorragie du post-partumMaladie de GaucherMisoprostolPost-partum hemorrhagePregnancy

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