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Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
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Assessment of the Cardiovascular System II: Inspection01:29

Assessment of the Cardiovascular System II: Inspection

Inspection is the initial step in assessing the cardiovascular system. It involves a detailed visual examination that provides crucial information about a patient's circulatory and cardiac health. This systematic process, conducted from head to toe, helps identify signs of cardiovascular conditions by observing physical appearance, skin and mucous membranes, jugular and carotid pulsations, chest symmetry, and the condition of the extremities.
Head and Neck
Drug Toxicity: Allergic Reactions01:30

Drug Toxicity: Allergic Reactions

Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial exposure to a...
Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

Overview

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Related Experiment Videos

Cutaneous alerts in systemic malignancy: part I.

M Yuste-Chaves1, P Unamuno-Pérez

  • 1Servicio de Dermatología, Hospital Universitario de Salamanca, Salamanca, Spain. manuelayuste@hotmail.com

Actas Dermo-Sifiliograficas
|April 13, 2013
PubMed
Summary
This summary is machine-generated.

Cutaneous signs and symptoms can indicate underlying malignancy, aiding early cancer diagnosis. This review details various skin conditions that may signal cancer or increased risk, emphasizing the skin

Related Experiment Videos

Area of Science:

  • Dermatology
  • Oncology
  • Internal Medicine

Background:

  • The skin, being highly accessible, offers non-invasive insights into systemic diseases.
  • Cutaneous manifestations are often overlooked in the context of internal malignancy.
  • While classic paraneoplastic syndromes are well-documented, other skin conditions can also indicate malignancy.

Purpose of the Study:

  • To familiarize dermatologists and clinicians with cutaneous signs and symptoms indicative of underlying malignancy.
  • To highlight the diagnostic value of skin examination in detecting cancer.
  • To present a range of skin conditions associated with malignancy or increased cancer risk.

Main Methods:

  • Review of medical literature on cutaneous manifestations of internal malignancy.
  • Classification of skin conditions based on clinical morphology.
  • Grouping of conditions by their most characteristic features.

Main Results:

  • A wide spectrum of skin conditions, beyond classic paraneoplastic syndromes, can signal malignancy.
  • Skin examination provides valuable, non-invasive information for diagnosing systemic disease.
  • Conditions are presented in groups based on morphology for clarity.

Conclusions:

  • Dermatologists and clinicians should consider skin examination as a crucial tool for early cancer diagnosis.
  • Recognizing diverse cutaneous signs can lead to the detection of underlying malignancies.
  • Various skin conditions serve as important indicators of cancer risk.