Related Experiment Video
Updated: May 12, 2026
Intraoperative Ultrasound in Spinal Surgery
Published on: August 17, 2022
A case of intradural osteosarcoma of the spine
Matt D Schiller1, Ralph J Mobbs, S Fiona Bonar
1Faculty of Medicine, University of New South Wales, Sydney, New South Wales 2052, Australia; Department of Neurosurgery, Prince of Wales Hospital, Sydney, New South Wales, Randwick 2031, Australia. matt@unsw.edu.au
Background Context:
Intradural-extramedullary spinal tumors and extradural osteosarcomas are both rare entities. Only one case of primary intradural-extramedullary osteosarcoma of the spine has been previously reported. This is the second reported case.
Purpose:
To describe a case of primary intradural-extramedullary osteosarcoma of the spine associated with rapid clinical deterioration.
Study Design:
Case report of a 70-year-old woman who presented with a constellation of neurologic symptoms.
Methods:
Review of patient files, radiographic studies, surgical images, histopathology, and relevant literature.
Results:
The patient underwent tumor debulking but exhibited rapid, postsurgical, functional deterioration and died within 6 weeks. This case and the only previous case of its kind both occurred in individuals with a remote history of iophendylate (Myodil) myelogram.
Conclusions:
Primary intradural-extramedullary extraosseous osteosarcoma of the spine is an exceedingly rare entity with no established management approach. Iophendylate myelography may be implicated in the etiology of this tumor type.
