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Updated: May 12, 2026

Treatment of Osteochondral Defects in the Rabbit's Knee Joint by Implantation of Allogeneic Mesenchymal Stem Cells in Fibrin Clots
Published on: May 21, 2013
Fibrin glue as a non-invasive outpatient treatment for post-arthroscopic knee seromas
David J Berkoff1, Matthew Kanaan, Ganesh Kamath
1Department of Orthopaedics, University of North Carolina Chapel Hill, Chapel Hill, NC 27599, USA. david_berkoff@med.unc.edu
Abstract:
Post-surgical seromas and cysts have been reported across many surgical subspecialties including orthopaedics. Treatments include both invasive surgical approaches and more recently reported non-invasive techniques. Non-invasive approaches currently include compressive wrapping, vasopneumatic cryotherapy, and motion exercises. Persistent lesions have been treated with talc or doxycycline sclerodesis. This case presents a patient with a post-arthroscopic seroma that was treated with fibrin glue in an outpatient setting. Fibrin glue has not been reported in the post-arthroscopy outpatient setting to address cystic lesions. This case suggests a viable non-invasive treatment option for these lesions. Level of evidence V.
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