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Updated: May 12, 2026

Production and Visualization of Bacterial Spheroplasts and Protoplasts to Characterize Antimicrobial Peptide Localization
Published on: August 11, 2018
Effects of antimicrobial peptide revealed by simulations: translocation, pore formation, membrane corrugation and
Licui Chen1, Nana Jia, Lianghui Gao
1Key Laboratory of Theoretical and Computational Photochemistry, Ministry of Education,College of Chemistry, Beijing Normal University, Beijing 100875, China. lhgao@bnu.edu.cn.
Abstract:
We explore the effects of the peripheral and transmembrane antimicrobial peptides on the lipid bilayer membrane by using the coarse grained Dissipative Particle Dynamics simulations. We study peptide/lipid membrane complexes by considering peptides with various structure, hydrophobicity and peptide/lipid interaction strength. The role of lipid/water interaction is also discussed. We discuss a rich variety of membrane morphological changes induced by peptides, such as pore formation, membrane corrugation and Euler buckling.
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