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Related Experiment Video

Updated: May 12, 2026

A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion
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Permanent cortical blindness after bronchial artery embolization.

Colette S van Doorn1, Diederick W De Boo2, Els J M Weersink3

  • 1Department of Radiology, Academic Medical Centre, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.

Cardiovascular and Interventional Radiology
|April 13, 2013
PubMed
Summary

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Massive hemoptysis treatment via bronchial artery embolization (BAE) led to permanent blindness in a cystic fibrosis patient due to an unexpected artery connection. This case highlights risks of embolization in patients with complex vascular anatomy.

Area of Science:

  • Interventional Radiology
  • Vascular Surgery
  • Neurology

Background:

  • Cystic fibrosis patients may experience massive hemoptysis.
  • Bronchial artery embolization (BAE) is a treatment for hemoptysis.

Observation:

  • A 35-year-old cystic fibrosis patient presented with massive hemoptysis.
  • CTA revealed a hypertrophied right upper lobe bronchial artery with active bleeding.
  • BAE was performed due to significant shunting to the pulmonary artery.

Findings:

  • Immediately post-BAE, the patient developed bilateral cortical blindness.
  • Angiography identified an unvisualized anastomosis between the bronchial artery and the right subclavian artery.
  • Embolization material refluxed into the posterior circulation via this anastomosis, causing permanent blindness.

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Implications:

  • This case underscores the critical importance of meticulous pre-procedural vascular assessment.
  • Unforeseen anastomoses can lead to catastrophic complications during embolization procedures.
  • Awareness of potential arterial connections is vital for patient safety in interventional radiology.