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Related Concept Videos

Drug Therapy01:28

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Drug Toxicity: Risk factors01:24

Drug Toxicity: Risk factors

Adverse Drug Reactions (ADRs) are potential complications that arise during pharmacotherapy, influenced by multiple risk factors. Age plays a significant role; both neonates and the elderly are at heightened risk due to their respective immature and diminished metabolic and elimination processes. Gender also impacts ADRs, with females experiencing a 1.5 to 1.7-fold greater risk than males, which may be linked to pharmacokinetic, pharmacodynamic, and hormonal differences. Notably, neonates, the...
Factors Influencing Drug Absorption: Disease States and Pharmacology01:25

Factors Influencing Drug Absorption: Disease States and Pharmacology

Multiple disease states can significantly influence the oral drug absorption process by affecting blood flow and the functionality of the gastrointestinal (GI) system. Various GI diseases, including conditions that alter GI motility, such as diarrhea, decreased acid secretions (achlorhydria), and infections, have been associated with reduced drug absorption.
Substances such as alcohol and specific drugs, including antineoplastics, can also negatively impact drug absorption. For instance,...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
Drug Abuse and Addiction: Pharmacological Phenomena01:15

Drug Abuse and Addiction: Pharmacological Phenomena

Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not necessarily...

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Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
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Published on: April 12, 2021

Patient characteristics associated with medication adherence.

Sharon J Rolnick1, Pamala A Pawloski, Brita D Hedblom

  • 1HealthPartners Research Foundation; 8170 33rd Ave. S.; MS 21111R; Bloomington, MN 55425, USA. Cheri.J.Rolnick@healthpartners.com

Clinical Medicine & Research
|April 13, 2013
PubMed
Summary

Patient medication adherence varies significantly across diseases, with lower rates observed in diabetes and asthma. Understanding patient characteristics is key to improving adherence and reducing healthcare costs.

Keywords:
Medication AdherencePatient CompliancePharmacy Benefits

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Area of Science:

  • Health Services Research
  • Clinical Pharmacy
  • Public Health

Background:

  • Medication adherence is crucial for therapeutic success, yet non-adherence is common, leading to increased morbidity and healthcare expenses.
  • Understanding factors influencing patient adherence is essential for developing targeted interventions.

Purpose of the Study:

  • To assess patient characteristics associated with medication adherence across eight prevalent chronic diseases.
  • To identify variations in adherence rates among different conditions and patient demographics.

Main Methods:

  • Retrospective analysis of electronic health records and pharmacy data from an integrated health system.
  • Calculation of medication possession ratios (MPR ≥80%) for over 31,000 patients across eight conditions.
  • Statistical analysis including bivariate associations and logistic regression to identify predictors of adherence.

Main Results:

  • Medication adherence was higher in males, Caucasians, older patients, and those in higher socioeconomic areas.
  • Adherence increased with lower comorbidity and a higher number of prescribed medications.
  • Lowest adherence rates were observed for diabetes (51%) and asthma (33%).

Conclusions:

  • The study found significant variations in medication adherence by disease and patient characteristics, challenging assumptions of high adherence with enhanced access.
  • There is a substantial need for improvement in medication adherence, particularly for patients with diabetes and asthma.
  • Further research and targeted interventions are required to address the identified disparities in adherence.