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Nephrotic syndrome associated with meningioma
P P Zachariah1, A Mathew, R Rajesh
1Department of Nephrology, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, India.
Indian Journal of Nephrology
|April 13, 2013
Summary
Recurrent meningioma in a patient with nephrotic syndrome resolved spontaneously after tumor removal. This case highlights a potential link between meningioma and nephrotic syndrome, suggesting surgical intervention may induce remission.
Area of Science:
- Neurosurgery
- Nephrology
- Oncology
Background:
- A 58-year-old male presented with a recurrent frontal meningioma and concurrent nephrotic syndrome.
- Nephrotic syndrome is characterized by edema, hypoalbuminemia, and proteinuria.
Observation:
- The patient experienced rapid neurological deterioration, precluding a renal biopsy.
- Surgical resection of the frontal meningioma was performed.
Findings:
- Following tumor resection, the patient exhibited spontaneous improvement in nephrotic syndrome symptoms within 4 weeks.
- Edema resolved, serum albumin levels increased, and proteinuria significantly decreased.
Implications:
- This case suggests a potential paraneoplastic association between meningioma and nephrotic syndrome.
- Surgical management of meningioma may lead to remission of associated nephrotic syndrome, warranting further investigation.
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