Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

Cancer Therapies

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...

Treatment Resistant Cancers

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Prognostic Reclassification and Survival Outcomes in Intermediate-Risk and Poor-Risk Nonseminomatous Germ Cell Tumors: Single-Institution Experience From Western India.

JCO global oncology·2026

Same author

Unveiling the variations in penile cancer care: identifying knowledge gaps and research priorities.

BMJ oncology·2026

Same author

Bladder Adjuvant Radiotherapy: Phase III Multicenter Randomized Controlled Trial of Adjuvant Radiotherapy or Observation for Postcystectomy Muscle-Invasive Bladder Cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology·2026

Same author

Prognostic Factors in Oropharyngeal Cancer Treated With Definitive Chemoradiotherapy.

Cancer medicine·2026

Same author

Pattern of resistance on first-line EGFR-directed therapy in EGFR-positive metastatic NSCLC.

Ecancermedicalscience·2026

Same author

Contemporary management of adrenocortical carcinoma: A narrative review.

Urologic oncology·2026

Search research articles

Related Experiment Videos

Sebaceous carcinoma and systemic chemotherapy.

Poonam Joshi¹, Amit Joshi, Vanita Norohna

¹Department of Head & Neck Surgery, Tata Memorial Hospital, Mumbai, Maharashtra, India.

Indian Journal of Medical and Paediatric Oncology : Official Journal of Indian Society of Medical & Paediatric Oncology

|April 13, 2013

Summary

Sebaceous gland carcinoma, a rare cancer, can spread to distant sites like the lungs. This case shows chemotherapy can achieve long-term remission in metastatic sebaceous gland carcinoma.

Keywords:

Chemotherapy lung metastasis sebaceous carcinoma

Related Experiment Videos

Area of Science:

Oncology
Dermatopathology

Background:

Sebaceous gland carcinoma is a rare malignancy originating from sebaceous gland epithelium.
Its variable presentation stems from widespread sebaceous gland distribution.

Observation:

A case of recurrent, extraocular sebaceous carcinoma in the left occipital region with lung metastases is presented.
The patient experienced complete remission following chemotherapy for lung metastasis.

Findings:

Metastatic sebaceous carcinoma can respond effectively to systemic chemotherapy.
Combination chemotherapy regimens may induce durable remission in advanced cases.

Implications:

Chemotherapy is an evolving and potentially effective treatment modality for metastatic sebaceous carcinoma.
This case highlights the potential for long-term disease control with chemotherapy in advanced sebaceous gland carcinoma.