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Published on: December 23, 2022
Warfarin-induced calciphylaxis successfully treated with sodium thiosulphate
Juber Hafiji1, Patrick Deegan, Rebecca Brais
1Skin Cancer Institute, Dermatological Surgical Unit, Tauranga, New Zealand. juber.hafiji@hotmail.co.uk
Abstract:
Calciphylaxis is a rare life-threatening form of skin necrosis. Although traditionally observed in patients with end-stage renal disease and/or hyperparathyroidism, calciphylaxis has also been reported to occur in 'non-traditional' patients with normal renal and parathyroid function. We report a case of warfarin-induced calciphylaxis treated successfully with sodium thiosulphate and discuss the role of Vitamin K2 as a potential therapeutic option in the management of warfarin-induced calciphylaxis.
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