Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants01:18

Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants

Oral anticoagulants are vital tools in preventing and treating blood clotting disorders. This diverse class of medications can be categorized as vitamin K antagonists, exemplified by warfarin, and direct thrombin inhibitors (DTIs), such as dabigatran, as well as factor Xa inhibitors, including rivaroxaban.
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
Urinary Tract Calculi IV: Nutrition Therapy and Prevention01:27

Urinary Tract Calculi IV: Nutrition Therapy and Prevention

Management of renal calculi focuses on effective strategies like tailored nutrition and hydration therapy. Adjusting diet and fluid intake reduces stone formation and recurrence, making these interventions simple yet powerful in kidney stone prevention and management.Understanding Kidney StonesKidney stones form when calcium, oxalate, uric acid, and cystine concentrate and crystallize in urine. Factors contributing to their formation include genetic predisposition, certain medical conditions,...
Anticoagulant Drugs: Low-Molecular-Weight Heparins01:30

Anticoagulant Drugs: Low-Molecular-Weight Heparins

Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
Urinary Tract Calculi III: Medical Management01:30

Urinary Tract Calculi III: Medical Management

The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A disease progression model comparing the long-term mobility and respiratory outcomes of adults with late-onset Pompe disease receiving cipaglucosidase alfa plus miglustat versus alglucosidase alfa.

Journal of comparative effectiveness research·2026
Same author

Structure, Electrochemistry, and Phase Evolution of Al-Substituted Na<sub>2/3</sub>[Ni<sub>1/3‑y</sub>Mn<sub>2/3‑z</sub>Al <sub><i>y</i>+<i>z</i></sub> ]O<sub>2</sub> as a Sodium-Ion Battery Cathode Material.

Chemistry of materials : a publication of the American Chemical Society·2026
Same author

Multimodal phenotypic clustering predicts cardiac outcomes in Fabry disease.

Orphanet journal of rare diseases·2026
Same author

Long-term efficacy and safety of pegunigalsidase alfa administered every 4 weeks in adults with Fabry disease: results from up to 5 years of the BRIGHT F51 phase III, open-label extension study.

Orphanet journal of rare diseases·2026
Same author

Maternal and Fetal Outcomes in Imiglucerase-Treated Patients With Gaucher Disease: Real-World Evidence From the International Collaborative Gaucher Group (ICGG) Gaucher Registry Pregnancy Sub-Registry.

Journal of inherited metabolic disease·2026
Same author

Diagnosis, management and monitoring of patients with Pompe disease in the UK.

BMJ neurology open·2025

Related Experiment Video

Updated: May 12, 2026

Treatment Protocol for Rotator Cuff Calcific Tendinitis Using a Single-Crystal Piezoelectric Focused Shock Wave Source
05:17

Treatment Protocol for Rotator Cuff Calcific Tendinitis Using a Single-Crystal Piezoelectric Focused Shock Wave Source

Published on: December 23, 2022

Warfarin-induced calciphylaxis successfully treated with sodium thiosulphate.

Juber Hafiji1, Patrick Deegan, Rebecca Brais

  • 1Skin Cancer Institute, Dermatological Surgical Unit, Tauranga, New Zealand. juber.hafiji@hotmail.co.uk

The Australasian Journal of Dermatology
|April 16, 2013
PubMed
Summary

Calciphylaxis, a rare skin necrosis, can occur in patients without kidney or parathyroid issues. This case highlights successful treatment of warfarin-induced calciphylaxis with sodium thiosulphate and suggests Vitamin K2 as a potential therapy.

Related Experiment Videos

Last Updated: May 12, 2026

Treatment Protocol for Rotator Cuff Calcific Tendinitis Using a Single-Crystal Piezoelectric Focused Shock Wave Source
05:17

Treatment Protocol for Rotator Cuff Calcific Tendinitis Using a Single-Crystal Piezoelectric Focused Shock Wave Source

Published on: December 23, 2022

Area of Science:

  • Dermatology
  • Nephrology
  • Pharmacology

Background:

  • Calciphylaxis is a rare, severe skin necrosis condition.
  • Traditionally linked to end-stage renal disease and hyperparathyroidism.
  • It can also occur in patients with normal renal and parathyroid function.

Observation:

  • A case of warfarin-induced calciphylaxis is presented.
  • This condition developed in a patient without traditional risk factors.
  • The patient had normal renal and parathyroid function.

Findings:

  • Successful treatment of warfarin-induced calciphylaxis was achieved using sodium thiosulphate.
  • Vitamin K2 is proposed as a potential therapeutic agent for managing this condition.
  • This suggests novel treatment avenues for non-traditional calciphylaxis cases.

Implications:

  • Sodium thiosulphate offers a viable treatment for warfarin-induced calciphylaxis.
  • Vitamin K2 may play a crucial role in preventing or treating calciphylaxis, especially in warfarin users.
  • Further research into Vitamin K2's role could lead to improved patient outcomes and management strategies for this rare disease.