A monoclonal antibody to platelet glycoprotein IIb induces aggregation of platelet rich plasma

P Perutelli1, P Marchese, P G Mori

  • 1Divisione di Ematologia e Oncologia, Istituto G. Gaslini, Genova, Italy.

Haematologica
|March 1, 1990
PubMed

The monoclonal antibody (MAb) GAP 5.9 directed against platelet glycoprotein IIb is described. This MAb is able to induce aggregation of platelet rich plasma in the absence of further stimuli and likely recognizes a glycoprotein epitope not closely related to calcium binding sites on the molecule.